blog posts Study: Telehealth services for the elderly should include caregivers Jan 24, 2022 4:30 pm270 views Family caregivers are often involved in the day-to-day activities of their older relatives, such as communicating with doctors, helping them navigate the health care system and making decisions that affect their care. When the pandemic hit, forcing health care systems to switch to telehealth visits, many of the caregivers who would have been involved in in-person care were left out of the process, according to a new observational study published in the Annals of Family Medicine. Overweight dogs respond well to high-protein, high-fiber diet Jan 24, 2022 9:00 am519 views A study of overweight dogs fed a reduced calorie, high-protein, high-fiber diet for 24 weeks found that the dogs’ body composition and inflammatory markers changed over time in ways that parallel the positive changes seen in humans on similar diets. The dogs achieved a healthier weight without losing too much muscle mass, and their serum triglycerides, insulin and inflammatory markers all decreased with weight loss. CRISPR-Cas13 targets proteins causing ALS, Huntington's disease in the mouse nervous system Jan 19, 2022 1:15 pm1990 views A new study by University of Illinois Urbana-Champaign researchers used a targeted CRISPR technique in the central nervous systems of mice to turn off production of mutant proteins that can cause ALS and Huntington’s disease. Rather than the popular DNA-editing CRISPR-Cas9 technique, the new approach uses CRISPR-Cas13, which can target mRNA – the messenger molecule that carries protein blueprints transcribed from DNA. The Illinois team developed Cas13 systems that could target and cut RNAs that code for the proteins that trigger ALS and Huntington’s disease, effectively silencing the genes without disturbing the cell’s DNA. Does our place in society influence how we respond to COVID-19 protocol? Dec 23, 2021 11:15 am1350 views University of Illinois Urbana-Champaign electrical and computer engineering professor Lav Varshney is a co-author of a new study that explores how social capital influences choices regarding COVID-19 mitigation compliance. Illinois News Bureau physical sciences editor Lois Yoksoulian spoke with Varshney about the lessons learned from this study and how they may help in other public health crises. How can we identify, respond to pandemic-triggered mental health crises? Dec 23, 2021 7:30 am983 views Social work professor Tara Powell discusses the U.S. surgeon general's recent advisory about a looming mental health crisis among the country's youths in the wake of the coronavirus pandemic. Models predict optimal airplane seating for reduced viral transmission Dec 21, 2021 9:45 am3168 views As airline ticket sales have soared during the holiday season and the omicron variant causes surges of COVID-19 cases, a new University of Illinois Urbana-Champaign study may help passengers and airlines reduce risk of COVID-19 transmission by optimally seating passengers to minimize potential virus spread. Researchers used the most current data on aerosol spread on airplanes to calculate optimal seating assignments for common Boeing aircraft at different capacities. Gene mutation leads to epileptic encephalopathy symptoms, neuron death in mice Dec 17, 2021 9:00 am799 views Mice with a genetic mutation seen in patients with epileptic encephalopathy, a severe form of congenital epilepsy, exhibit not only the seizure, developmental and behavioral symptoms of the disorder, but also neural degeneration and inflammation in the brain, University of Illinois Urbana-Champaign researchers found in a new study. The findings highlight the mutation as an important part of the disease’s pathology and a potential target for treatment. Atomic structure of antifungal drug confirms unusual mechanism, opens door to less-toxic derivatives Dec 9, 2021 10:15 am822 views Advanced molecular imaging technology has now mapped the structure of a drug widely used to treat fungal infections but whose workings have mystified researchers and physicians for nearly 70 years. In a new study, researchers at the University of Illinois Urbana-Champaign, the University of Wisconsin, Madison and the National Institutes of Health described in atomistic detail the structure of the drug amphotericin B, a powerful but toxic antifungal agent. Seeing the structure provides illumination in the researchers’ quest to formulate less-toxic AmB derivatives. Water disinfection byproduct disrupts reproductive hormones, damages pituitary in female mice Nov 24, 2021 8:00 am630 views A byproduct formed during water disinfection disrupts hormones in the brain that regulate the female reproductive cycle in mice and also damages cells in the pituitary gland, a new study from University of Illinois Urbana-Champaign researchers found. The new study’s findings of the chemical’s effects on reproductive regulation in the brain complement previous work that found that it also disrupts function in and causes damage to ovary cells, indicating the chemical could impact the entire reproductive system. The researchers hope that the continued study of these effects can help establish a safe level of exposure to guide future regulations. PFAS exposure, high-fat diet drive prostate cells’ metabolism into pro-cancer state Nov 11, 2021 10:00 am1133 views Consuming a high-fat diet along with exposure to PFAS changes benign and malignant prostate cells, promoting rapid tumor growth, scientists at the University of Illinois found in mouse study. Scientists discover how antibiotics penetrate Gram-negative bacterial cell walls Nov 8, 2021 8:00 am1339 views Scientists have labored for decades to find antibiotics that work against Gram-negative bacteria, which cause some of the deadliest infections in hospital settings and are most likely to be resistant to treatment with existing antibiotics. In a study reported in the journal Chemical Science, researchers developed a new method to determine how antibiotics with specific chemical properties thread their way through tiny pores in the otherwise impenetrable cell envelopes of Gram-negative bacteria. Do kids need a COVID-19 vaccine? Nov 4, 2021 9:00 am1221 views The availability of a COVID-19 vaccine for school-aged children offers protection for children as well as eases challenges faced by their families and their schools, says Rebecca Lee Smith, an epidemiologist at the University of Illinois Urbana-Champaign. New molecule targets, images and treats lung cancer tumors in mice Oct 25, 2021 10:00 am1028 views Lung cancer can be elusive to spot and difficult to treat, but University of Illinois Urbana-Champaign researchers have developed a finely tuned molecular agent that can precisely target lung and other cancer cells for imaging and treatment. Patients view perinatal depression screenings as ineffective, study finds Oct 13, 2021 9:00 am849 views A standardized protocol and patient-centered approach are needed to improve perinatal depression screenings so patients feel the screenings are useful and effective, a new study found. Wu earns NIH Director's New Innovator Award Oct 5, 2021 9:45 am3593 views Biochemistry professor Nicholas Wu has received a 2021 NIH Director’s New Innovator Award. His project aims to understand how antibodies interact with their targets. DNA sensor quickly determines whether viruses are infectious Sep 22, 2021 1:00 pm2557 views A new sensor can detect not only whether a virus is present, but whether it’s infectious – an important distinction for containing viral spread. Researchers demonstrated the sensor, which integrates specially designed DNA fragments and nanopore sensing, with two key viruses that cause infections worldwide: the human adenovirus and the virus that causes COVID-19. Antibodies from original strain COVID-19 infection don't bind to variants, study finds Sep 17, 2021 8:30 am4944 views People infected with the original strain of the virus that causes COVID-19 early in the pandemic produced a consistent antibody response, making two main groups of antibodies to bind to the spike protein on the virus’s outer surface. However, those antibodies don’t bind well to newer variants, a new study from the University of Illinois Urbana-Champaign found. Avocados change belly fat distribution in women, controlled study finds Sep 3, 2021 9:00 am38298 views An avocado a day could help redistribute belly fat in women toward a healthier profile, according to a new study from the University of Illinois Urbana-Champaign and collaborators. One hundred and five adults with overweight and obesity participated in a randomized controlled trial that provided one meal a day for 12 weeks. Women who consumed avocado as part of their daily meal had a reduction in deeper visceral abdominal fat. Can people take a livestock drug to treat a deadly virus? Sep 2, 2021 10:00 am16013 views Taking large or multiple doses of the anti-parasitic drug ivermectin can cause a toxic overdose, and humans should not take forms intended for animal use, says Illinois veterinary medicine expert Dr. Jim Lowe. Latinos' beliefs about social status may affect their cardiovascular health, study finds Aug 19, 2021 8:45 am573 views Subjective perceptions of their social status may have stronger effects on the cardiovascular health of Hispanics and Latinos in the U.S. than objective markers such as income, according to a new study led by Lissette Piedra. Light can trigger key signaling pathway for embryonic development, cancer Aug 17, 2021 12:45 pm3797 views Blue light is illuminating new understanding of a key signaling pathway in embryo development, tissue maintenance and cancer genesis. Illinois researchers developed a method that makes membrane-bound receptors reactive to light, triggering the Wnt pathway. Study: Domestic control of COVID-19 takes priority over international travel bans Aug 11, 2021 8:00 am817 views A new paper co-written by University of Illinois Urbana-Champaign economist Yilan Xu says taming domestic transmission of COVID-19 ought to be prioritized over international travel bans. Study identifies molecule that stimulates muscle-building Aug 9, 2021 8:00 am2855 views In a randomized control study of 10 healthy young men, researchers compared how consuming the single amino acid leucine or its two-molecule equivalent, dileucine, influenced muscle-building and breakdown. They found that dileucine boosts the metabolic processes that drive muscle growth 42% more than free leucine does. Study offers insight into underlying causes of seizure disorder in babies Aug 3, 2021 7:00 am737 views Researchers report that infantile spasms, a rare but serious seizure disorder in babies, appear to be the result of a molecular pathway gone awry. In their study of a mouse model of the disorder, the researchers discovered that genetic mutations associated with the disease impair a pathway that is involved in building new synapses in the hippocampus, a brain region essential to learning and memory. What impact do the Olympics and mass-sporting events have on public health? Aug 2, 2021 8:15 am1563 views Attending high-profile and mass-participation sporting events may increase individuals’ physical activity levels and enhance their emotional well-being, according to Mikihiro Sato, a professor of recreation, sport and tourism. Study tests microplasma against middle-ear infections Jul 29, 2021 8:00 am456 views In a new study, researchers explore the use of microplasma – a highly focused stream of chemically excited ions and molecules – as a noninvasive method for attacking the bacterial biofilms that resist antibiotic treatment in the middle ear. New approach eradicates breast cancer in mice Jul 21, 2021 1:00 pm23454 views A new approach to treating breast cancer kills 95-100% of cancer cells in mouse models of human estrogen-receptor-positive breast cancers and their metastases in bone, brain, liver and lungs. The newly developed drug, called ErSO, quickly shrinks even large tumors to undetectable levels. 2020 deadlier than previous five years, even with COVID-19 numbers removed, study finds Jul 19, 2021 1:30 pm1916 views An upswing in death rates from non-COVID-19 causes in 2020 hit hard for men ages 15-64, according to a new study by computer science professor Sheldon H. Jacobson and internal medicine professor Janet Jokela. University of Illinois receives APLU award for COVID-19 testing program Jul 1, 2021 2:00 pm2413 views The University of Illinois Urbana-Champaign has received the inaugural Research Response to Community Crisis Award from the Association of Public and Land-grant Universities for its COVID-19 testing program. Frequent COVID-19 testing key to efficient, early detection, study finds Jun 30, 2021 8:30 am1908 views The chance of detecting the virus that causes COVID-19 increases with more frequent testing, no matter the type of test, a new study found. Both polymerase chain reaction and antigen tests, paired with rapid results reporting, can achieve 98% sensitivity if deployed at least every three days. Consistent bedtime routines in infancy improve children's sleep habits through age 2 Jun 29, 2021 1:45 pm554 views Consistent bedtime routines and activities such as reading books beginning when infants are 3 months old promote better sleep habits through age 2, according to a study by researchers at the Family Resiliency Center. DNAzymes could outperform protein enzymes for genetic engineering Jun 24, 2021 8:15 am1333 views Move over, gene-editing proteins – there’s a smaller, cheaper, more specific genetic engineering tool on the block: DNAzymes – small DNA molecules that can function like protein enzymes. Researchers at the University of Illinois Urbana-Champaign have developed a technique that, for the first time, allows DNAzymes to target and cut double-stranded DNA, overcoming a significant limitation of the technology. Cancer survivors' tongues less sensitive to tastes than those of healthy peers Jun 23, 2021 9:15 am929 views Head and neck cancer survivors' tongues are less sensitive to bitter, salty and sweet tastes, and this taste dysfunction lasts for years, University of Illinois Urbana-Champaign scientists found in a new study. Combining three techniques boosts brain-imaging precision Jun 23, 2021 7:00 am931 views Researchers have developed a method to combine three brain-imaging techniques to more precisely capture the timing and location of brain responses to a stimulus. Model helps predict, analyze decision-making on adopting Type 2 diabetes medical guidelines Jun 14, 2021 8:45 am939 views A new computational framework incorporates social interactions to analyze how best to communicate about new medical guidelines to encourage their adoption. Cholesterol metabolite induces production of cancer-promoting vesicles Jun 9, 2021 8:00 am722 views Scientists report that a byproduct of cholesterol metabolism causes some cells to send out cancer-promoting signals to other cells. These signals are packaged in membrane-bound compartments called extracellular vesicles. Why do we need a health care equity law? Jun 3, 2021 8:30 am799 views The Illinois Health Care and Human Services Reform Act has potential to address root causes of health disparities and foster health equity through provisions such as implicit bias training and community health workers, says Illinois professor Ruby Mendenhall. Geology helps map kidney stone formation from tiny to troublesome May 25, 2021 1:00 pm1677 views Advanced microscope technology and cutting-edge geological science are giving new perspectives to an old medical mystery: How do kidney stones form, why are some people more susceptible to them and can they be prevented? Portable, affordable, accurate, fast: Team invents new COVID-19 test May 18, 2021 4:00 am2058 views A new coronavirus test can get accurate results from a saliva sample in less than 30 minutes, researchers report in the journal Nature Communications. Many of the components of the hand-held device used in this technology can be 3D-printed, and the test can detect as little as one viral particle per 1-microliter drop of fluid. Intoxication brings strangers physically closer, study finds May 10, 2021 2:00 pm916 views In a study with pandemic-related implications, researchers report that strangers who consume alcohol together may keep their distance initially – but draw physically closer as they become intoxicated. No previous studies have tested the effects of alcohol consumption on social distance, the researchers say. They report the new findings in the Proceedings of the National Academy of Sciences. Mantis shrimp-inspired camera provides second opinion during cancer surgery May 5, 2021 1:00 pm1714 views Some of the world’s greatest innovations, such as Leonardo da Vinci’s flying machine, owe their strength and elegance to natural design. Researchers from the University of Illinois Urbana-Champaign have returned their gaze to the natural world to develop a camera inspired by the mantis shrimp that can visualize cancer cells during surgery. Team builds better tool for assessing infant brain health Apr 29, 2021 12:00 am693 views Researchers have created a new, open-access tool that allows doctors and scientists to evaluate infant brain health by assessing the concentration of various chemical markers, called metabolites, in the brain. The tool compiled data from 140 infants to determine normal ranges for these metabolites. Study finds green spaces linked to lower racial disparity in COVID-19 infection rates Apr 28, 2021 10:15 am1101 views A new study is the first to examine the relationship between the supply of green spaces and reduced racial disparity in infectious disease rates. Geographies of death: Study maps COVID-19 health disparities in Greater Santiago Apr 27, 2021 9:00 am409 views People up to age 40 living in economically depressed municipalities in the Greater Santiago, Chile, metropolitan area were three times more likely to die as a result of the infection than their counterparts in wealthier areas, researchers report in the journal Science. COVID-19 mobility restrictions effective for short duration, study finds Apr 22, 2021 12:00 pm678 views Attempts at restricting people’s mobility to control the spread of COVID-19 may be effective only for a short period, researchers said. A new study examines people’s mobility for seven months during the pandemic in the United States using publicly available, anonymized mobile phone data. K-12 Shield Playbook offers guidance for reopening schools amid ongoing pandemic Apr 14, 2021 2:15 pm1053 views A new resource is available to help guide teachers and school administrators as they reopen schools amid the ongoing COVID-19 pandemic, assembled by researchers and experts at the University of Illinois Urbana-Champaign. The K-12 Shield Playbook is based on the SHIELD Illinois program used to mitigate the COVID-19 pandemic at the university. Young adults may provide care for older relatives much more frequently than thought Apr 12, 2021 9:30 am710 views Young adults and teens may provide care for adult relatives much more often than previously thought, according to a new study, though they worry about detriments to educational or career goals and would like more training and support. Study links prenatal phthalate exposure to altered information processing in infants Apr 6, 2021 7:30 am19043 views Researchers have found evidence linking pregnant women’s exposure to phthalates to altered cognitive outcomes in their infants. Machine learning helps spot gait problems in individuals with multiple sclerosis Mar 26, 2021 11:00 am2371 views Monitoring the progression of multiple sclerosis-related gait issues can be challenging in adults over 50 years old, requiring a clinician to differentiate between problems related to MS and other age-related issues. To address this problem, researchers are integrating gait data and machine learning to advance the tools used to monitor and predict disease progression. More protein doesn't mean more strength in resistance-trained middle-aged adults Mar 25, 2021 7:30 am3262 views A 10-week muscle-building and dietary program involving 50 middle-aged adults found no evidence that eating a high-protein diet increased strength or muscle mass more than consuming a moderate amount of protein while training. The intervention involved a standard strength-training protocol with sessions three times per week. None of the participants had previous weightlifting experience.