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  • New analytical technique helps researchers spot subtle differences in subcellular chemistry

    Portrait of the researchers that participated in the study

    Chemists from the University of Illinois Urbana-Champaign are testing the limits of analytical chemistry by rapidly detecting subtle changes in cellular chemistry in an effort to boost early disease intervention. From left, professor Stanislav Rubakhin, molecular and integrative physiology graduate research assistant Dan Castro, professor Jonathan Sweedler, professor Elena Romanova and bioengineering graduate research assistant Yuxuan Richard Xie.

    Photo by L. Brian Stauffer


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  • Editor’s notes:

    To reach Jonathan Sweedler, call 217-244-7359; email

    The paper “Image-guided MALDI mass spectrometry for high-throughput single- organelle characterization” is available online and from the U. of I. News Bureau.

    DOI: 10.1038/s41592-021-01277-2.