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  • Team finds promising new drug target for Alzheimer's disease

    Molecular and integrative biology professors Yang (Kevin) Xiang, Charles Cox and their colleagues found a potential new drug target for the treatment of Alzheimer's disease.

    Molecular and integrative biology professors Yang (Kevin) Xiang, Charles Cox and their colleagues found a potential new drug target for the treatment of Alzheimer's disease.

    Photo by L. Brian Stauffer

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      Molecular and integrative biology professors Yang (Kevin) Xiang, Charles Cox and their colleagues found a potential new drug target for the treatment of Alzheimer's disease.

      Photo by L. Brian Stauffer

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      The beta-2 adrenergic receptor (green) spans the cell membrane (orange and blue). In this visualization, a binding pocket in the receptor interacts with a beta-blocker (red, gray and blue molecule near the center). The new study found that amyloid-beta, a protein fragment linked to the detrimental effects of Alzheimer's disease, binds to a different region on the beta-2 adrenergic receptor.

      Public domain image; more information.

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