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  • Team solves decades-old molecular mystery linked to blood clotting

    An interdisciplinary collaboration at the University of Illinois led to a breakthrough in understanding blood clotting. Researchers on the study were (from left): Emad Tajkhorshid, Chad Rienstra, Mary Clay, Rebecca Davis-Harrison, Zenmei Ohkubo, Narjes Tavoosi, Mark Arcario, Taras Pogorelov and James Morrissey.

    An interdisciplinary collaboration at the University of Illinois led to a breakthrough in understanding blood clotting. Researchers on the study were (from left): Emad Tajkhorshid, Chad Rienstra, Mary Clay, Rebecca Davis-Harrison, Zenmei Ohkubo, Narjes Tavoosi, Mark Arcario, Taras Pogorelov and James Morrissey.

    Photo by L. Brian Stauffer

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      An interdisciplinary collaboration at the University of Illinois led to a breakthrough in understanding blood clotting. Researchers on the study were (from left): Emad Tajkhorshid, Chad Rienstra, Mary Clay, Rebecca Davis-Harrison, Zenmei Ohkubo, Narjes Tavoosi, Mark Arcario, Taras Pogorelov and James Morrissey.

      Photo by L. Brian Stauffer

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      Watch a movie of the supercomputer simulation of the blood clotting factor interacting with the membrane. The GLA domain of the clotting factor is depicted as a purple tube; individual GLA amino acids are yellow; tightly bound calcium ions are pink spheres; and the interacting phospholipids that make up the membrane are below.

      Courtesy Emad Tajkhorshid

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