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  • Team deciphers how myotonic dystrophy generates lethal heart dysfunctions

    Researchers determined key molecular events that lead to heart abnormalities in myotonic dystrophy. The team included, from left, bioengineering professor Lawrence Dobrucki, postdoctoral fellow Jamila Hedhli, biochemistry professor Auinash Kalsotra, graduate student Sushant Bangru, research scientist Chaitali Misra and graduate student Kin Lam.

    Researchers determined key molecular events that lead to heart abnormalities in myotonic dystrophy. The team included, from left, bioengineering professor Lawrence Dobrucki, postdoctoral fellow Jamila Hedhli, biochemistry professor Auinash Kalsotra, graduate student Sushant Bangru, research scientist Chaitali Misra and graduate student Kin Lam.

    Photo by L. Brian Stauffer

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  • Editor’s notes: 
    To reach Auinash Kalsotra, call 217-300-7654; email kalsotra@illinois.edu.

    The paper "Aberrant expression of a non-muscle RBFOX2 isoform triggers cardiac conduction defects in myotonic dystrophy" is available online and from the U. of I. News Bureau.

    DOI: 10.1016/j.devcel.2020.01.037