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  • Study offers insight into underlying causes of seizure disorder in babies

    Photo of researchers.

    Researchers, from left, Kwan Young Lee, Nien-Pei Tsai and their colleagues discovered that a gene mutation associated with infantile spasms disrupts the formation of synapses in the hippocampus, a brain structure essential to learning and memory. They also tested a potential drug compound in a mouse model of infantile spasms that reversed some of the negative physiological and behavioral effects.

    Photo by L. Brian Stauffer


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  • Editor’s notes

    To reach Nien-Pei Tsai, email

    The paper “Infantile spasms-linked Nedd4-2 mediated hippocampal plasticity and learning via cofilin signaling” is available online and from the U. of I. News Bureau.

    DOI: 10.15252/embr.202152645