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  • Mice study suggests metabolic diseases may be driven by gut microbiome, loss of ovarian hormones

    Illinois scientists Erik Nelson, Kelly Swanson and Brett Loman

    Mice that received fecal implants from donors that had their ovaries removed gained more fat mass and had greater expression of liver genes associated with inflammation, Type 2 diabetes, fatty liver disease and atherosclerosis. The findings may shed light on the greater incidence of metabolic dysfunction in postmenopausal women. The team members included, from left: molecular and integrative physiology professor Erik R. Nelson; Kelly Swanson, the director of the Division of Nutritional Sciences and the Kraft Heinz Endowed Professor in Human Nutrition; and animal sciences professor Brett R. Loman.

    Photo by Fred Zwicky


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  • Editor’s Note: To reach Kelly S. Swanson, email


    The paper “Gut microbiome responds to alteration in female sex hormone status and exacerbates metabolic dysfunction” is available online or from the News Bureau.

    DOI: 10.1080/19490976.2023.2295429