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  • First test of anti-cancer agent PAC-1 in human clinical trials shows promise

    Photo of U. of I. researchers.

    Illinois professor of veterinary clinical medicine Dr. Timothy Fan, left, and chemistry professor Paul Hergenrother. The U. of I. team found that the compound PAC-1 has therapeutic potential in pet dogs with spontaneously occurring cancers. The animal studies set the stage for the human clinical trials.

    Photo by Fred Zwicky


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  • Editor’s notes:   

    To reach Dr. Arkadiusz Dudek, email

    To reach Dr. Oana Danciu, email

    To reach Paul Hergenrother, email

    To reach Timothy Fan, email

    The paper “Phase I study of procaspase-activating compound-1 (PAC-1) in the treatment of advanced malignancies” is available online and from the U. of I. News Bureau.

    DOI: 10.1038/s41416-022-02089-7