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  • Antibiotic breakthrough: Team discovers how to overcome gram-negative bacterial defenses

    Researchers have found a way to penetrate the cell wall of gram-negative bacteria, overcoming a major barrier to the development of new broad-spectrum antibiotics.

    Researchers have found a way to penetrate the cell wall of gram-negative bacteria, overcoming a major barrier to the development of new broad-spectrum antibiotics. The team includes, from left, U. of I. graduate student Alfredo Garcia, graduate student Riley Svec, chemistry professor Paul Hergenrother, graduate student Bryon Drown, graduate student Michelle Richter and postdoctoral researcher Andrew Riley.

    Photo by L. Brian Stauffer

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  • Editor’s notes:
    To reach Paul Hergenrother, call 217-333-0363; email hergenro@illinois.edu.
    The paper “Predictive compound accumulation rules yield a broad-spectrum antibiotic” is available online and from the U. of I. News Bureau.
    DOI: 10.1038/nature22308