News Bureau

By hijacking a cancer cell’s own metabolism, researchers have found a way to tag and target elusive cancers with small-molecule sugars. This opens treatment pathways for cancers that are not responsive to conventional targeted antibodies, such as triple-negative breast cancer.

Encouraging children to drink water with their school lunches could prevent more than half a million cases of child obesity and overweight -- and trim the medical and societal costs by more than $13 billion, a new study suggests.

A new study has uncovered the genetic processes that link insufficient protein consumption during pregnancy with the development of muscle problems in mothers and their male offspring.

A class of molecules formed when the body metabolizes omega-3 fatty acids could inhibit cancer’s growth and spread, University of Illinois researchers report in a new study in mice.

A small, thin square of an organic plastic that can detect disease markers in breath or toxins in a building’s air could soon be the basis of portable, disposable sensor devices. By riddling the thin plastic films with pores, University of Illinois researchers made the devices sensitive enough to detect at levels that are far too low to smell, yet are important to human health.

Healthy mass transit systems could contribute to healthier communities, according to a new study by University of Illinois researchers that determined higher mass transit use was correlated with lower obesity rates in counties across the United States.

A new study links anxiety, a brain structure called the orbitofrontal cortex, and optimism, finding that healthy adults who have larger OFCs tend to be more optimistic and less anxious.

Childhood trauma could affect the trajectory of multiple sclerosis development and response to treatment in adulthood, a new study in mice found.

Mice that had experienced stress when young were more likely to develop the autoimmune disorder and less likely to respond to a common treatment, researchers at the University of Illinois Urbana-Champaign found. However, treatment that activated an immune-cell receptor mitigated the effects of childhood stress in the mice.

CHAMPAIGN, Ill. – A new surgical tool that uses light to make sure surgeons removing cancerous tumors “got it all” was found to correlate well with traditional pathologists’ diagnoses in a clinical study, showing that the tool could soon enable reliable, real-time guidance for surgeons.

One measurement of key biomarkers in blood that characterize sepsis can give physicians as much information as hours of monitoring symptoms, a new study found.

A proof-of-concept study conducted in a mouse model of Alzheimer’s disease offers new evidence that copper isotopes can be used to detect the amyloid-beta protein deposits that form in the brains of people living with – or at risk of developing – Alzheimer’s.

Fred A. Kummerow, a pioneer in the study of dietary contributors to heart disease who led a decades-long crusade to remove trans fats from the food supply, died Wednesday, May 31, at his home in Urbana, Illinois. He was 102.

Global health authorities are frantically pursuing a vaccine against the novel coronavirus in the hope that it will allow everyone to get back to a pre-COVID-19 reality ASAP. Thomas O’Rourke, a professor emeritus of community health, says those expectations are probably overblown.

Scientists have labored for decades to find antibiotics that work against Gram-negative bacteria, which cause some of the deadliest infections in hospital settings and are most likely to be resistant to treatment with existing antibiotics. In a study reported in the journal Chemical Science, researchers developed a new method to determine how antibiotics with specific chemical properties thread their way through tiny pores in the otherwise impenetrable cell envelopes of Gram-negative bacteria.

Some of the world’s greatest innovations, such as Leonardo da Vinci’s flying machine, owe their strength and elegance to natural design. Researchers from the University of Illinois Urbana-Champaign have returned their gaze to the natural world to develop a camera inspired by the mantis shrimp that can visualize cancer cells during surgery.

Drinking water not only keeps children hydrated, but also increases their ability to multitask, suggests a new study by researchers at the University of Illinois and their collaborators.

Third-graders who spend a class session in a natural outdoor setting are more engaged and less distracted in their regular classroom afterward than when they remain indoors, scientists found in a new study.

Monitoring the progression of multiple sclerosis-related gait issues can be challenging in adults over 50 years old, requiring a clinician to differentiate between problems related to MS and other age-related issues. To address this problem, researchers are integrating gait data and machine learning to advance the tools used to monitor and predict disease progression.

Preschoolers may express awareness about body-image issues – but their parents may miss opportunities to promote positive body-image formation in their children because parents believe them to be too young to have these concerns, new research suggests.

A new sensor can detect not only whether a virus is present, but whether it’s infectious – an important distinction for containing viral spread. Researchers demonstrated the sensor, which integrates specially designed DNA fragments and nanopore sensing, with two key viruses that cause infections worldwide: the human adenovirus and the virus that causes COVID-19.  

A search committee established to find the Carle Illinois College of Medicine’s inaugural dean will begin its work this month with the goal of naming the dean by spring 2016

A new study reveals a previously unknown mechanism that governs whether viruses that infect bacteria will quickly kill their hosts or remain latent inside the cell. The discovery, reported in the journal eLife, also may apply to viruses that infect humans and other animals, the researcher said.

Head and neck cancer survivors' tongues are less sensitive to bitter, salty and sweet tastes, and this taste dysfunction lasts for years, University of Illinois Urbana-Champaign scientists found in a new study.

People who viewed sex as a leisure activity used their pandemic downtime to engage in more  frequent, creative and satisfying sex, U. of I. professor Liza Berdychevsky found in a recent survey. 

A multidisciplinary team at the University of Illinois Urbana-Champaign has devised a new approach to 3D imaging that captures DNA methylation, a key epigenetic change associated with learning in the brain. The scientists say their proof-of-concept study in pigs will easily translate to humans, as the new method relies on standard MRI technology and biological markers already in use in human medicine.

Cheryl Hanley-Maxwell will join the University of Illinois at Urbana-Champaign as dean of the College of Applied Health Sciences effective Aug. 16, pending approval by the University of Illinois Board of Trustees.

While all of the “Big Five” personality traits – agreeableness, conscientiousness, extraversion, neuroticism and openness – are related to experiencing stress, neuroticism showed the strongest link, according to research co-written by Bo Zhang, a professor of labor and employment relations and of psychology at Illinois.

By peering at the brains of study subjects prompted to suppress negative emotions, scientists have gained new insights into how emotional regulation influences negative feelings and memories. They hope the findings will lead to new methods to combat depression.

A Minute With™... Fred Kummerow, trans fat expert

The chance of detecting the virus that causes COVID-19 increases with more frequent testing, no matter the type of test, a new study found. Both polymerase chain reaction and antigen tests, paired with rapid results reporting, can achieve 98% sensitivity if deployed at least every three days.

Consuming high amounts of carbohydrates and various forms of sugar during the year prior to treatment for head and neck cancer may increase patients’ risks of cancer recurrence and mortality, a new study reports.

CHAMPAIGN, Ill. - Writers, outdoor enthusiasts and leaf-peeping tourists have known for centuries that nature has restorative powers that reduce feelings of stress and promote a sense of tranquility.

Dietary fiber found in grains is a large component of many diets, but little is understood about how we digest the fiber, as humans lack enzymes to break down the complex molecules. Some species of gut bacteria break down the fiber in such a way that it not only becomes digestible, but releases ferulic acid, an important antioxidant with multiple health benefits, according to a new study led by researchers at the University of Illinois Urbana-Champaign.

Researchers are sending tiny drug-laden nanoparticles on a mission to seek and destroy cancer stem cells.

Researchers have developed a new antibiotic that reduced or eliminated drug-resistant bacterial infections in mouse models of acute pneumonia and sepsis while sparing healthy microbes in the mouse gut. The drug, called lolamicin, also warded off secondary infections with Clostridioides difficile, a common and dangerous hospital-associated bacterial infection, and was effective against more than 130 multidrug-resistant bacterial strains in cell culture.

A new study found that 24-month-old children who spent less than 60 minutes looking at screens each day and those who engaged in daily physical activity had better executive function than their peers. Executive function includes the ability to remember, plan, pay attention, shift between tasks and regulate one's thoughts and behavior.

Growing muscle tissue on grooved platforms helps neurons more effectively integrate with the muscle, a requirement for engineering muscle in the lab that responds and functions like muscle in the body, University of Illinois researchers found in a new study.

It took a small group of researchers only four years – a blink of an eye in pharmaceutical terms – to scour a collection of 10,000 bacterial strains and isolate the genes responsible for making 19 unique, previously unknown phosphonate natural products, researchers report. Each of these products is a potential new drug. One of them has already been identified as an antibiotic.

March through May saw a significant increase in deaths over previous years – and not just from COVID-19, says a new study from the University of Illinois at Urbana-Champaign.

When deaths attributed to COVID-19 were removed from the Centers for Disease Control and Prevention totals, the death rate in several demographics outpaced the same period in 2019, the study found. The timeframe represents the first three months of response to the COVID-19 pandemic in the United States.

A new study reveals that people with tinnitus who are less bothered by their symptoms use different brain regions when processing emotional information.

Graphene-based biosensors could usher in an era of liquid biopsy, detecting DNA cancer markers circulating in a patient’s blood or serum. But current designs need a lot of DNA. In a new study, crumpling graphene makes it more than ten thousand times more sensitive to DNA by creating electrical “hot spots,” researchers at the University of Illinois at Urbana-Champaign found.

Researchers can look into your eyes to determine whether you’re getting your lutein, a pigment found in green leafy vegetables that is known to accumulate in the brain. Two new studies find that children with higher lutein levels in the eye tend to do better than others on tests of cognition and academic achievement, even after accounting for other factors known to influence academic performance such as IQ, gender, body composition and physical fitness.

Flexibility, personalization and increased consumption of protein and fiber were key in optimizing dieters’ weight-loss success on the Individualized Diet Improvement Program, created by University of Illinois Urbana-Champaign food scientists.

A new CRISPR gene-editing method can inactivate one of the genes responsible for an inherited form of ALS, scientists at the University of Illinois at Urbana-Champaign report in a new study. The novel treatment slowed disease progression, improved muscle function and extended lifespan in mice with an aggressive form of ALS.

A diet including daily avocado consumption improves the ability to focus attention in adults with overweight and obesity, a new randomized control trial found.

CHAMPAIGN, Ill. — Researchers have found an easy way to produce carbon nanoparticles that are small enough to evade the body’s immune system, reflect light in the near-infrared range for easy detection, and carry payloads of pharmaceutical drugs to targeted tissues.

A new point-of-care rapid-sensing device can detect a key marker of eye injury in minutes – a time frame crucial to treating eye trauma.  

University of Illinois researchers developed a gel laden with gold nanoparticles that changes color when it reacts with a teardrop containing ascorbic acid, released from a wound to the eye. In a new study published in the journal Biosensors and Bioelectronics, the researchers used the sensor, called OjoGel, to measure ascorbic acid levels in artificial tears and in clinical samples of fluid from patients’ eyes. 

Artificial intelligence, building-block chemistry and a molecule-making machine teamed up to find the best general reaction conditions for synthesizing chemicals important to biomedical and materials research – a finding that could speed innovation and drug discovery as well as make complex chemistry automated and accessible.

Researchers at the University of Illinois Urbana-Champaign and collaborators in Poland and Canada reported their findings in the journal Science.

Researchers studied the effects of a 12-week exercise regimen on 148 active-duty Air Force airmen, half of whom also received a twice-daily nutrient beverage that included protein; the omega-3 fatty acid, DHA; lutein; phospholipids; vitamin D; B vitamins and other micronutrients; along with a muscle-promoting compound known as HMB. Both groups improved in physical and cognitive function, with added gains among those who regularly consumed the nutritional beverage, the team reports.

The University of Illinois Urbana-Champaign has received the inaugural Research Response to Community Crisis Award from the Association of Public and Land-grant Universities for its COVID-19 testing program.