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  • Researchers at the University of Illinois worked with physicians at Carle Foundation Hospital in a new study that found one measurement of biomarkers in the blood can predict a patient’s sepsis status as well as monitoring the patient for hours. Pictured, from left: Professors Rashid Bashir and Ruoqing Zhu, Prenosis Inc. employee Ishan Taneja and professor Sihai Dave Zhao.

    Study: Biomarkers as predictive of sepsis as lengthy patient monitoring

    One measurement of key biomarkers in blood that characterize sepsis can give physicians as much information as hours of monitoring symptoms, a new study found.

  • Yee Ming Khaw stands on the left, Makoto Inoue stands on the right.

    Childhood trauma could affect development, treatment of multiple sclerosis, mouse study finds

    Childhood trauma could affect the trajectory of multiple sclerosis development and response to treatment in adulthood, a new study in mice found.

    Mice that had experienced stress when young were more likely to develop the autoimmune disorder and less likely to respond to a common treatment, researchers at the University of Illinois Urbana-Champaign found. However, treatment that activated an immune-cell receptor mitigated the effects of childhood stress in the mice.

  • Portrait of Thomas O'Rourke. He is wearing a dark red shirt and smiling.

    Will a coronavirus vaccine be a cure-all?

    Global health authorities are frantically pursuing a vaccine against the novel coronavirus in the hope that it will allow everyone to get back to a pre-COVID-19 reality ASAP. Thomas O’Rourke, a professor emeritus of community health, says those expectations are probably overblown.

  • Feeling anxious? Check your orbitofrontal cortex and cultivate your optimism, study suggests

    A new study links anxiety, a brain structure called the orbitofrontal cortex, and optimism, finding that healthy adults who have larger OFCs tend to be more optimistic and less anxious.

  • Ming Kuo and her colleagues found that student engagement in the classroom improved after an outdoor lesson.

    Lessons in nature boost classroom engagement afterward, researchers report

    Third-graders who spend a class session in a natural outdoor setting are more engaged and less distracted in their regular classroom afterward than when they remain indoors, scientists found in a new study.

  • Committee to identify, recruit founding dean for Carle Illinois College of Medicine

    A search committee established to find the Carle Illinois College of Medicine’s inaugural dean will begin its work this month with the goal of naming the dean by spring 2016

  • Photo of Mani Nakamura and his co-authors professor emeritus John Erdman, alumna Catherine Applegate and graduate student Mindy Lee

    Study: Individualized eating program helps dieters lose weight, keep it off

    An individualized diet plan developed by nutritionists at the U. of I. shows promise at helping users lose weight and keep it off. The program uses a visual tool that encourages dieters to select foods high in protein and fiber.

  • An artist's rendering of viruses passing through a nanopore sensor

    DNA sensor quickly determines whether viruses are infectious

    A new sensor can detect not only whether a virus is present, but whether it’s infectious – an important distinction for containing viral spread. Researchers demonstrated the sensor, which integrates specially designed DNA fragments and nanopore sensing, with two key viruses that cause infections worldwide: the human adenovirus and the virus that causes COVID-19.  

  • Drinking more water improves children’s ability to multitask, according to a new study led by Illinois professor Naiman Khan.

    Drinking more water improves multitasking ability in children, study finds

    Drinking water not only keeps children hydrated, but also increases their ability to multitask, suggests a new study by researchers at the University of Illinois and their collaborators.

  • Young children develop body image much earlier than parents believe, suggests a new study led by Janet Liechty, a professor of social work and of medicine at the University of Illinois. Co-authors of the paper were Julie P. Birky, a clinical counselor at the Counseling Center, and social work graduate student Samantha Clarke, both of the U. of I.; and University of Michigan communication studies professor Kristen Harrison.

    Preschoolers form body images – but parents are unaware, study says

    Preschoolers may express awareness about body-image issues – but their parents may miss opportunities to promote positive body-image formation in their children because parents believe them to be too young to have these concerns, new research suggests.

  • Group portrait of researchers Manuel Hernandez, Rachneet Kaur and Richard Sowers.

    Machine learning helps spot gait problems in individuals with multiple sclerosis

    Monitoring the progression of multiple sclerosis-related gait issues can be challenging in adults over 50 years old, requiring a clinician to differentiate between problems related to MS and other age-related issues. To address this problem, researchers are integrating gait data and machine learning to advance the tools used to monitor and predict disease progression.

  • Mikihiro Sato, professor of recreation, sport and tourism

    What impact do the Olympics and mass-sporting events have on public health?

    Attending high-profile and mass-participation sporting events may increase individuals’ physical activity levels and enhance their emotional well-being, according to Mikihiro Sato, a professor of recreation, sport and tourism.

  • Hanley-Maxwell named College of Applied Health Sciences dean

    Cheryl Hanley-Maxwell will join the University of Illinois at Urbana-Champaign as dean of the College of Applied Health Sciences effective Aug. 16, pending approval by the University of Illinois Board of Trustees.

  • Viruses may inject their DNA into a host cell synchronously or randomly, a new study finds. The difference appears to influence the course of infection.

    Discovery: Mechanical properties of viral DNA determine the course of infection

    A new study reveals a previously unknown mechanism that governs whether viruses that infect bacteria will quickly kill their hosts or remain latent inside the cell. The discovery, reported in the journal eLife, also may apply to viruses that infect humans and other animals, the researcher said.

  • photo of researchers Stephane Lezmi, Huan Wang and Yuan-Xiang Pan New research by, from left, nutritional sciences professor Stphane Lezmi, doctoral researcher Huan Wang and Yuan-Xiang Pan, a professor of nutritional sciences and of food science, found the long-sought link between maternal protein deficiency during pregnancy and problems such as stunted growth and metabolic diseases in offspring.

    Maternal protein deficiency during pregnancy ‘memorized’ by fetal muscle cells

    A new study has uncovered the genetic processes that link insufficient protein consumption during pregnancy with the development of muscle problems in mothers and their male offspring.

  • Illustration showing fentanyl pills, a syringe, an ambulance and a chunk of crystal methamphetamine.

    Study finds 'staggering increase' in methamphetamine deaths tied to opioid co-use

    The U.S. methamphetamine mortality rate increased fiftyfold between 1999 and 2021, with most of the added deaths also involving heroin or fentanyl, researchers report in the American Journal of Public Health.

  • Viewing 3-D videos of tree-lined residential streets significantly aids in people's recovery from stressful events, according to research by lecturer Bin Jiang (right) and professor William C. Sullivan, both in the department of landscape architecture. (Not pictured) Linda Larsen, an instructor of English, and landscape architecture graduate student Dongying Li were co-authors on a paper about the study.

    Watching 3-D videos of trees helps people recover from stress, researchers say

    CHAMPAIGN, Ill. - Writers, outdoor enthusiasts and leaf-peeping tourists have known for centuries that nature has restorative powers that reduce feelings of stress and promote a sense of tranquility.

  • Illinois researchers developed nanoparticles that can target cancer stem cells (yellow), the rare cells within a tumor (blue) that can cause cancer to recur or spread.

    Drug-delivering nanoparticles seek and destroy elusive cancer stem cells

    Researchers are sending tiny drug-laden nanoparticles on a mission to seek and destroy cancer stem cells.

  • Psychology professor Sanda Dolcos and graduate student Yuta Katsumi explore how suppressing negative emotions affects brain function and memory.

    Emotional suppression reduces memory of negative events

    By peering at the brains of study subjects prompted to suppress negative emotions, scientists have gained new insights into how emotional regulation influences negative feelings and memories. They hope the findings will lead to new methods to combat depression.

  • University of Illinois food science and human nutrition professor Anna E. Arthur found in a new study that a carbohydrate-restricted, higher fat diet may reduce cancer recurrence and mortality rates among people with squamous-cell head and neck cancers.

    Study explores carbohydrates’ impact on head, neck cancers

    Consuming high amounts of carbohydrates and various forms of sugar during the year prior to treatment for head and neck cancer may increase patients’ risks of cancer recurrence and mortality, a new study reports.

  • An Illinois student provides a saliva sample for a COVID-19 test.

    Frequent COVID-19 testing key to efficient, early detection, study finds

    The chance of detecting the virus that causes COVID-19 increases with more frequent testing, no matter the type of test, a new study found. Both polymerase chain reaction and antigen tests, paired with rapid results reporting, can achieve 98% sensitivity if deployed at least every three days.

  • As shown in this artist’s rendering, grooved surfaces help muscle grow into aligned fibers, which provides a track for neurons to follow.

    Feeling groovy: Neurons integrate better with muscle grown on grooved platforms

    Growing muscle tissue on grooved platforms helps neurons more effectively integrate with the muscle, a requirement for engineering muscle in the lab that responds and functions like muscle in the body, University of Illinois researchers found in a new study.

  • Sheldon Jacobson and Janet Jokela stand outdoors.

    Study of non-COVID-19 deaths shows 2020 increase in several demographics

    March through May saw a significant increase in deaths over previous years – and not just from COVID-19, says a new study from the University of Illinois at Urbana-Champaign.

    When deaths attributed to COVID-19 were removed from the Centers for Disease Control and Prevention totals, the death rate in several demographics outpaced the same period in 2019, the study found. The timeframe represents the first three months of response to the COVID-19 pandemic in the United States.

  • Genome mining effort discovers 19 new natural products in four years

    It took a small group of researchers only four years – a blink of an eye in pharmaceutical terms – to scour a collection of 10,000 bacterial strains and isolate the genes responsible for making 19 unique, previously unknown phosphonate natural products, researchers report. Each of these products is a potential new drug. One of them has already been identified as an antibiotic.

  • Fred Kummerow

    100-year-old trans fat pioneer celebrates news of an FDA ban

    A Minute With™... Fred Kummerow, trans fat expert

  • In two new studies, University of Illinois kinesiology and community health professor Naiman Khan, postdoctoral researcher Anne Walk and their colleagues found links between levels of lutein in the eye and cognition and academic performance in pre-adolescent children.

    Studies link nutrient, academic achievement in pre-adolescent children

    Researchers can look into your eyes to determine whether you’re getting your lutein, a pigment found in green leafy vegetables that is known to accumulate in the brain. Two new studies find that children with higher lutein levels in the eye tend to do better than others on tests of cognition and academic achievement, even after accounting for other factors known to influence academic performance such as IQ, gender, body composition and physical fitness.

  • Research team photo

    Team uses MRI to image epigenetics in the brain

    A multidisciplinary team at the University of Illinois Urbana-Champaign has devised a new approach to 3D imaging that captures DNA methylation, a key epigenetic change associated with learning in the brain. The scientists say their proof-of-concept study in pigs will easily translate to humans, as the new method relies on standard MRI technology and biological markers already in use in human medicine.

  • In this computer simulation, DNA in a serum sample interacts with a crumpled graphene surface.

    Crumpled graphene makes ultra-sensitive cancer DNA detector

    Graphene-based biosensors could usher in an era of liquid biopsy, detecting DNA cancer markers circulating in a patient’s blood or serum. But current designs need a lot of DNA. In a new study, crumpling graphene makes it more than ten thousand times more sensitive to DNA by creating electrical “hot spots,” researchers at the University of Illinois at Urbana-Champaign found.

  • Illinois researchers demonstrated a CRISPR gene-editing technique that slowed the progression of ALS in mice. Pictured, from left: graduate student Colin Lim, professor Thomas Gaj, graduate student Michael Gapinske, professor Pablo Perez-Pinera.

    New CRISPR base-editing technology slows ALS progression in mice

    A new CRISPR gene-editing method can inactivate one of the genes responsible for an inherited form of ALS, scientists at the University of Illinois at Urbana-Champaign report in a new study. The novel treatment slowed disease progression, improved muscle function and extended lifespan in mice with an aggressive form of ALS.

  • Study: Emotion processing in the brain changes with tinnitus severity

    A new study reveals that people with tinnitus who are less bothered by their symptoms use different brain regions when processing emotional information.

  • A SHIELD worker explains the protocol for a COVID-19 saliva test at the University of Illinois.

    University of Illinois receives APLU award for COVID-19 testing program

    The University of Illinois Urbana-Champaign has received the inaugural Research Response to Community Crisis Award from the Association of Public and Land-grant Universities for its COVID-19 testing program.

  • An artist's rendering of an implant with the smart coating

    Smart surgical implant coatings provide early failure warning while preventing infection

    Newly developed “smart” coatings for surgical orthopedic implants can monitor strain on the devices to provide early warning of implant failures while killing infection-causing bacteria, University of Illinois Urbana-Champaign researchers report. The coatings integrate flexible sensors with a nanostructured antibacterial surface inspired by the wings of dragonflies and cicadas.

  • Photo of research team.

    Scientists discover how antibiotics penetrate Gram-negative bacterial cell walls

    Scientists have labored for decades to find antibiotics that work against Gram-negative bacteria, which cause some of the deadliest infections in hospital settings and are most likely to be resistant to treatment with existing antibiotics. In a study reported in the journal Chemical Science, researchers developed a new method to determine how antibiotics with specific chemical properties thread their way through tiny pores in the otherwise impenetrable cell envelopes of Gram-negative bacteria.

  • Portrait of psychology professor Aron Barbey

    Exercise and nutrition regimen benefits physical, cognitive health

    Researchers studied the effects of a 12-week exercise regimen on 148 active-duty Air Force airmen, half of whom also received a twice-daily nutrient beverage that included protein; the omega-3 fatty acid, DHA; lutein; phospholipids; vitamin D; B vitamins and other micronutrients; along with a muscle-promoting compound known as HMB. Both groups improved in physical and cognitive function, with added gains among those who regularly consumed the nutritional beverage, the team reports.

  • Researchers developed a rapid sensing gel to measure a molecular marker of eye injury in a teardrop. From left: Carle opthamologist Dr. Laura Labriola, Illinois visiting scholar Ketan Dighe and professor Dipanjan Pan.

    Color-changing sensor detects signs of eye damage in tears

    A new point-of-care rapid-sensing device can detect a key marker of eye injury in minutes – a time frame crucial to treating eye trauma.  

    University of Illinois researchers developed a gel laden with gold nanoparticles that changes color when it reacts with a teardrop containing ascorbic acid, released from a wound to the eye. In a new study published in the journal Biosensors and Bioelectronics, the researchers used the sensor, called OjoGel, to measure ascorbic acid levels in artificial tears and in clinical samples of fluid from patients’ eyes. 

  • Group portrait of researchers Wawrzyniec Dobrucki, Zhongmin Zhu, Viktor Gruev, Zuodong Liang, Steven Blair and Shuming Nie.

    Mantis shrimp-inspired camera provides second opinion during cancer surgery

    Some of the world’s greatest innovations, such as Leonardo da Vinci’s flying machine, owe their strength and elegance to natural design. Researchers from the University of Illinois Urbana-Champaign have returned their gaze to the natural world to develop a camera inspired by the mantis shrimp that can visualize cancer cells during surgery.

  • Fred Kummerow, a professor of comparative biosciences at the University of Illinois, continued his research for more than seven decades. Kummerow died May 31 at his home in Urbana.

    Fred A. Kummerow, successful crusader against trans fats, dies at 102

    Fred A. Kummerow, a pioneer in the study of dietary contributors to heart disease who led a decades-long crusade to remove trans fats from the food supply, died Wednesday, May 31, at his home in Urbana, Illinois. He was 102.

  • Professor Huimin Zhao led a team that achieved the highest reported efficiency of inserting genes into human cells with CRISPR-Cas9.

    For CRISPR, tweaking DNA fragments before inserting yields highest efficiency rates yet

    University of Illinois researchers achieved the highest reported rates of inserting genes into human cells with the CRISPR-Cas9 gene-editing system, a necessary step for harnessing CRISPR for clinical gene-therapy applications.

    By chemically tweaking the ends of the DNA to be inserted, the new technique is up to five times more efficient than current approaches. The researchers saw improvements at various genetic locations tested in a human kidney cell line, even seeing 65% insertion at one site where the previous high had been 15%.

  • An avocado a day improves the ability to focus attention for overweight or obese adults, Illinois researchers found in a new study.

    Study: Daily avocado consumption improves attention in persons with overweight, obesity

    A diet including daily avocado consumption improves the ability to focus attention in adults with overweight and obesity, a new randomized control trial found.

     

  • Professor Erik Procko stands with arms crossed.

    What is the new variant of coronavirus in the UK?

    New mutations to the coronavirus that causes COVID-19 are emerging, including one in the United Kingdom with higher infection rates that has sparked new travel bans. Erik Procko, a professor of biochemistry at the University of Illinois Urbana-Champaign, has been studying mutations in the spike protein, the part of the virus that binds to human cells. In an interview, Procko discussed the new variation and whether mutations to the spike protein could create resistance to vaccines or other treatments.

  • Portable device can quickly determine the extent of an eye injury

    An engineer and an ophthalmologist are working together to develop a portable sensor that can quickly and inexpensively determine whether an eye injury is mild or severe. The device, called OcuCheck, works by measuring levels of vitamin C in the fluids that coat or leak from the eye. The sensor could speed efforts to determine the extent of eye injuries at accident sites, in rural areas lacking ophthalmology specialists or on the battlefield, the researchers said.

  • Illinois researchers used ultrafast pulses of tailored light to make neurons fire in different patterns, the first example of coherent control in a living cell.

    Carefully crafted light pulses control neuron activity

    Specially tailored, ultrafast pulses of light can trigger neurons to fire and could one day help patients with light-sensitive circadian or mood problems, according to a new study in mice at the University of Illinois.

  • Photo of the researcher.

    In survey, COVID-19 vaccine recipients report changes in menstrual bleeding

    A new analysis of reports from more than 35,000 people offers the most comprehensive assessment so far of menstrual changes experienced by pre- and post-menopausal individuals in the first two weeks after receiving the COVID-19 vaccine. Published in the journal Science Advances, the study adds to the evidence that significant numbers of people experience this unexpected side effect.

  • Photo of research team standing together outside in front of a brick wall and building.

    Portable, affordable, accurate, fast: Team invents new COVID-19 test

    A new coronavirus test can get accurate results from a saliva sample in less than 30 minutes, researchers report in the journal Nature Communications. Many of the components of the hand-held device used in this technology can be 3D-printed, and the test can detect as little as one viral particle per 1-microliter drop of fluid.

  • University of Illinois postdoctoral researcher Prabuddha Mukherjee, left, bioengineering professors Rohit Bhargava and Dipanjan Pan, and postdoctoral researcher Santosh Misra report the development of a new class of carbon nanoparticles for biomedical use.

    Biomedical breakthrough: Carbon nanoparticles you can make at home

    CHAMPAIGN, Ill. — Researchers have found an easy way to produce carbon nanoparticles that are small enough to evade the body’s immune system, reflect light in the near-infrared range for easy detection, and carry payloads of pharmaceutical drugs to targeted tissues.

  • New research from engineers at the University of Illinois at Urbana-Champaign shows how oxygen transfer is altered in diseased lung tissue.

    New study shows how oxygen transfer is altered in diseased lung tissue

    A multidisciplinary team of researchers at the University of Illinois at Urbana-Champaign has developed tiny sensors that measure oxygen transport in bovine lung tissue. The study – which establishes a new framework for observing the elusive connection between lung membranes, oxygen flow and related disease – is published in the journal Nature Communications.

  • A synthetic DNA enzyme inserts into a cell membrane, causing lipids to shuffle between the inner and outer membrane layers.

    DNA enzyme shuffles cell membranes a thousand times faster than its natural counterpart

    A new synthetic enzyme, crafted from DNA rather than protein, flips lipid molecules within the cell membrane, triggering a signal pathway that could be harnessed to induce cell death in cancer cells. It is the first such synthetic enzyme to outperform its natural counterparts.

  • Researchers stand in the Molecule Maker Lab.

    Artificial intelligence and molecule machine join forces to generalize automated chemistry

    Artificial intelligence, building-block chemistry and a molecule-making machine teamed up to find the best general reaction conditions for synthesizing chemicals important to biomedical and materials research – a finding that could speed innovation and drug discovery as well as make complex chemistry automated and accessible.

    Researchers at the University of Illinois Urbana-Champaign and collaborators in Poland and Canada reported their findings in the journal Science.

  • Photo of Brian Monson

    Study compares third-trimester sound exposures in fetuses, premature infants

    A new study is the first to compare the sound exposures of fetuses in the last 16 weeks of pregnancy with their age-matched premature peers. The analysis reveals profound differences in their exposures to noise, language and the biological sounds of the mother, with implications for the infants’ development.

  • Illinois researchers developed a tiny thermometer to take fast temperatures inside of cells. Pictured, from left: Graduate student Jeffrey W. Brown; Rhanor Gillette, emeritus professor of molecular and integrative physiology; Sanjiv Sinha, professor of mechanical science and engineering; Daniel Llano, professor of molecular and integrative physiology. Front row: graduate student Manju Rajagopal.

    Tiny thermometer measures how mitochondria heat up the cell by unleashing proton energy

    Armed with a tiny new thermometer probe that can quickly measure temperature inside of a cell, University of Illinois researchers have illuminated a mysterious aspect of metabolism: heat generation.