News Bureau

In a collaborative effort between scientists and personnel on U.S. military bases in 31 states and Puerto Rico, researchers surveyed for an infection caused by an emerging fungal pathogen that afflicts snakes. The effort found infected snakes on military bases in 19 states and Puerto Rico, demonstrating that the fungus is more widely distributed than was previously known. The team reports the findings in the journal PLOS ONE.

A new antifungal molecule, devised by tweaking the structure of prominent antifungal drug Amphotericin B, has the potential to harness the drug’s power against fungal infections while doing away with its toxicity, researchers at the University of Illinois Urbana-Champaign and collaborators at the University of Wisconsin-Madison report in the journal Nature.

Acetaminophen is considered the safest over-the-counter pain reliever and fever reducer available during pregnancy and studies have shown that 50%-65% of women in North America and Europe take the analgesic during pregnancy. A new study from researchers at the University of Illinois Urbana-Champaign explored the relationship between acetaminophen use during pregnancy and language outcomes in early childhood. It found that increasing acetaminophen use was associated with language delays.

The chance of detecting the virus that causes COVID-19 increases with more frequent testing, no matter the type of test, a new study found. Both polymerase chain reaction and antigen tests, paired with rapid results reporting, can achieve 98% sensitivity if deployed at least every three days.

Fred A. Kummerow, a pioneer in the study of dietary contributors to heart disease who led a decades-long crusade to remove trans fats from the food supply, died Wednesday, May 31, at his home in Urbana, Illinois. He was 102.

A new study reveals a previously unknown mechanism that governs whether viruses that infect bacteria will quickly kill their hosts or remain latent inside the cell. The discovery, reported in the journal eLife, also may apply to viruses that infect humans and other animals, the researcher said.

The enormous, solitary leatherback sea turtle spends most of its long life at sea. After hatching and dispersing across the world’s oceans, only the female leatherbacks return to their natal beaches to lay clutches of eggs in the sand. A new study offers fresh insights into their nesting choices and will help efforts to prevent the extinction of this globally endangered giant of the sea, researchers said.

The popularity of bulldogs and other flat-faced pets is at an all-time high. According to the American Kennel Club, from 2006-2016, the number of registered bulldogs and French bulldogs in the U.S. increased by 60% and 476%, respectively. In 2023, the French bulldog topped the AKC’s most popular breeds list. University of Illinois Urbana-Champaign veterinary surgeon Dr. Heidi Phillips devotes much of her practice to treating the respiratory problems of flat-faced breeds like bulldogs. She argues for better breeding practices to avoid perpetuating the many health problems these breeds experience.

Dr. Leyi Wang and the University of Illinois Urbana-Champaign Veterinary Diagnostic Laboratory have played a key role in diagnosing coronavirus infection in animal species in zoos across the country. This is important work for understanding the virus’s spread and its broad host range, Wang says.

Childhood trauma could affect the trajectory of multiple sclerosis development and response to treatment in adulthood, a new study in mice found.

Mice that had experienced stress when young were more likely to develop the autoimmune disorder and less likely to respond to a common treatment, researchers at the University of Illinois Urbana-Champaign found. However, treatment that activated an immune-cell receptor mitigated the effects of childhood stress in the mice.

A class of molecules formed when the body metabolizes omega-3 fatty acids could inhibit cancer’s growth and spread, University of Illinois researchers report in a new study in mice.

Newly developed “smart” coatings for surgical orthopedic implants can monitor strain on the devices to provide early warning of implant failures while killing infection-causing bacteria, University of Illinois Urbana-Champaign researchers report. The coatings integrate flexible sensors with a nanostructured antibacterial surface inspired by the wings of dragonflies and cicadas.

In a new report, dozens of scientists, health practitioners and children’s health advocates are calling for renewed attention to the growing evidence that many common and widely available chemicals endanger neurodevelopment in fetuses and children of all ages.

In the fall of 2020, the University of Illinois Urbana-Champaign welcomed students back for in-person instruction amid the powerful first wave of the COVID-19 pandemic. The university successfully maintained operations throughout the semester – with zero COVID-19-related deaths or hospitalizations in the campus community – thanks to its “SHIELD: Target, Test, Tell” program. In a sweeping report, the team behind the campuswide collaboration details the innovations in modeling, saliva testing and results reporting that helped mitigate the spread of the virus, and shares the data collected and lessons learned through the process.

Clinical trials of the anti-cancer agent PAC-1 are continuing to expand, thanks to a $7 million angel investment from an anonymous contributor who originally invested $4 million to help get the compound this far in the drug-approval pipeline.

At the University of Illinois, an engineer teamed up with a veterinarian to test a bone cancer drug delivery system in animals bigger than the standard animal model, the mouse. They chose dogs – mammals closer in size and biology to humans – with naturally occurring bone cancers, which also are a lot like human bone tumors.

The first case of a novel strain of coronavirus has been confirmed in the United States. Virologist Leyi Wang, a professor of Veterinary Medicine at the University of Illinois, discussed the outbreak of the new strain with News Bureau biomedical sciences editor Liz Ahlberg Touchstone.

Just like humans, dogs are sometimes born with impaired hearing or experience hearing loss as a result of disease, inflammation, aging or exposure to noise. Dog owners and K-9 handlers ought to keep this in mind when adopting or caring for dogs, and when bringing them into noisy environments, researchers say.

A study of a herpes virus that infects chickens offers new insights into potentially problematic interactions between vaccines made from live viruses and the viruses they are meant to thwart.

CHAMPAIGN, Ill. - Advancements in the use of computed tomography (also known as CT) imaging by researchers at the University of Illinois Veterinary Teaching Hospital are enabling them to diagnose life-threatening conditions in dogs and cats faster, dramatically affecting the course, outcomes and costs of treatment.

A drug that spurs cancer cells to self-destruct has been cleared for use in a clinical trial of patients with anaplastic astrocytoma, a rare malignant brain tumor, and glioblastoma multiforme, an aggressive late-stage cancer of the brain. This phase Ib trial will determine if the experimental drug PAC-1 can be used safely in combination with a standard brain-cancer chemotherapy drug, temozolomide.

Point your phone or tablet at the poster with a cow image and a small 3-D cow appears before you – Desktop Bessie, with her skeleton, circulatory, digestive and nervous systems, and various organs visible as you move around her.

If you’re a veterinary student, the augmented reality cow is a great way to learn a cow’s anatomy.

Chemical compounds called cannabinoids are found in marijuana and also are produced naturally in the body from omega-3 fatty acids. A well-known cannabinoid in marijuana, THC, is responsible for some of its euphoric effects, but it also has anti-inflammatory benefits. A new study in animal tissue reveals the cascade of chemical reactions that convert omega-3 fatty acids into cannabinoids that have anti-inflammatory benefits – but without the psychotropic high. 

Only a few cells in a cancerous tumor are able to break away and spread to other parts of the body, but the curve along the edge of the tumor may play a large role in activating these tumor-seeding cells, according to a new University of Illinois study.

Celebrating the nation’s Independence Day with fireworks is an enduring tradition, but fireworks can be a source of distress and danger to wildlife. Dr. Sam Sander, a clinical professor of zoo and wildlife medicine at the University of Illinois Urbana-Champaign, spoke with News Bureau life sciences editor Diana Yates about how fireworks affect wildlife and the environment, and how to minimize the risks.

Influenza, SARS and COVID-19 are all zoonotic diseases, readily transmitted from animals to humans. The viruses that cause these diseases also share traits that allow them to quickly mutate, infect widely and spread around the world.

In a new podcast, a veterinarian and expert in zoonotic diseases offers insights into the special characteristics of the new coronavirus that make it more like influenza and less like SARS or the virus that causes the especially lethal Middle Eastern Respiratory Syndrome.

A phase I clinical trial of PAC-1, a drug that spurs programmed cell death in cancer cells, found only minor side effects in patients with end-stage cancers. The drug stalled the growth of tumors in the five people in the trial with neuroendocrine cancers and reduced tumor size in two of those patients. It also showed some therapeutic activity against sarcomas, scientists and clinicians report in the British Journal of Cancer.

Sending ailing dogs home with oral opioids may not be an effective way to manage their pain, experts report in a free, online continuing education program recently developed for veterinarians. In light of growing evidence that such drugs don’t work well in dogs – added to the fact that humans sometimes abuse opioids prescribed for pets – the common practice of prescribing oral opioids for dogs in pain should be reexamined, the experts say.

Anticipating the need among opioid prescribers for additional training to meet regulatory mandates, these experts created an online continuing education program that addresses the problem. The training includes cautions about unwarranted prescription of oral opioids and advice on effective pain management for veterinary patients. 

CHAMPAIGN, Ill. - Low-density lipoprotein (LDL), the "bad cholesterol" that doctors consider a sign of potential heart disease, is merely a marker of a diet lacking all of the essential amino acids, says University of Illinois comparative biosciences professor Fred Kummerow, 99, a longtime opponent of the medical establishment's war on cholesterol.

Rates of antibiotic-resistant infections in companion animals are rising at an alarming rate. An Illinois veterinarian discusses what can be done about it.

Researchers have found evidence linking pregnant women’s exposure to phthalates to altered cognitive outcomes in their infants.

Taking large or multiple doses of the anti-parasitic drug ivermectin can cause a toxic overdose, and humans should not take forms intended for animal use, says Illinois veterinary medicine expert Dr. Jim Lowe.