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  • University of Illinois professor Carl R. Woese discovered a new domain of life.

    Carl R. Woese, who discovered a new domain of life, dies at 84

    CHAMPAIGN, lll. - University of Illinois microbiology and Institute for Genomic Biology professor Carl R. Woese, who adopted a molecular approach to classifying organisms and upended taxonomy with the discovery of a "third domain" of life, died Sunday (Dec. 30) at his home in Urbana, Ill. He was 84.

  • Carl Woese receives the Crafoord Prize

    CHAMPAIGN, Ill. - Microbiologist Carl R. Woese formally accepted the $500,000 Crafoord Prize in Biosciences from the Royal Swedish Academy of Sciences in Sweden. The king of Sweden presented the prize to Woese on Sept. 24.

  • Carl Woese wins the Crafoord Prize in Biosciences, given by the Royal Academy

    CHAMPAIGN, Ill. - Microbiologist Carl R. Woese today won the $500,000 Crafoord Prize in Biosciences given by the Royal Swedish Academy of Sciences. The annual prize marks accomplishments in scientific fields not covered by the Nobel Prizes in science, which the academy also selects. The king of Sweden will present the prize to Woese Sept. 24 in Stockholm.

  • Carl Woese wins the Crafoord Prize in Biosciences, given by the Royal Academy

    CHAMPAIGN, Ill. - Microbiologist Carl R. Woese today won the $500,000 Crafoord Prize in Biosciences given by the Royal Swedish Academy of Sciences. The annual prize marks accomplishments in scientific fields not covered by the Nobel Prizes in science, which the academy also selects. The king of Sweden will present the prize to Woese Sept. 24 in Stockholm.

  • The research team sits and stands together as a group in a research setting.

    CAR-T immune therapy attacks ovarian cancer in mice with a single dose

    CAR-T immune therapies could be effective against solid tumors if the right targets are identified, a new study led by University of Illinois Urbana-Champaign researchers suggests. The researchers successfully deployed CAR-T in a mouse model of ovarian cancer, a type of aggressive, solid-tumor cancer that has eluded such therapies until now.

  • Carver Trust grant to advance molecular studies at Illinois

    CHAMPAIGN, Ill. - Rapidly advancing tools let researchers amass oceans of biological data - so much so that fishing out the meaning is as daunting as climbing a mountain without gear. A new $3.15 million, three-year grant from the Roy J. Carver Charitable Trust, however, will make the University of Illinois at Urbana-Champaign a national leader in its capability to analyze molecular information about cells, officials say.

  • University of Illinois chemists led by professor Christina White (center) developed a new catalyst based on the metal manganese that is both highly reactive and highly selective, traits previously thought to be inversive. Graduate students, from left: Shauna Paradine, Shannon Miller, Jinpeng Zhao, Aaron Petronico and Jennifer Griffin.

    Catalyst combining reactivity and selectivity could speed drug development

    Chemists have long believed that inserting nitrogen – a beneficial ingredient for making many pharmaceuticals and other biologically active molecules – into a carbon-hydrogen bond requires a trade-off between catalyst reactivity and selectivity. But a new manganese-based catalyst developed by University of Illinois chemists has given researchers both in one efficient, lower-cost package.

  • The navel orangeworm caterpillar works with a fungus to overcome plant chemical defenses, a new study finds.

    Caterpillar, fungus in cahoots to threaten fruit, nut crops, study finds

    New research reveals that Aspergillus flavus, a fungus that produces carcinogenic aflatoxins that can contaminate seeds and nuts, has a multilegged partner in crime: the navel orangeworm caterpillar, which targets some of the same nut and fruit orchards afflicted by the fungus. Scientists report in the Journal of Chemical Ecology that the two pests work in concert to overcome plant defenses and resist pesticides.

  • Nohra Mateus-Pinilla, left, a wildlife veterinary epidemiologist at the University of Illinois Prairie Research Institute, with graduate student Shannon Fredebaugh, led a study that found that cats spread disease to wildlife even in remote parts of a 1,500-acre natural area. Mateus-Pinilla is a researcher with the Illinois Natural History Survey, one of the surveys in the PRI.

    Cats pass disease to wildlife, even in remote areas

    CHAMPAIGN, lll. - Researchers tracking the spread of Toxoplasma gondii - a parasite that reproduces only in cats but sickens and kills many other animals - have found infected wildlife throughout a 1,500-acre (600-hectare) natural area in central Illinois.

  • University of Illinois microbiology professor Rachel Whitaker and her colleagues found two groups of nearly identical microbes that were diverging into different species.

    Caught in the act: Team discovers microbes speciating

    CHAMPAIGN, lll. - Not that long ago in a hot spring in Kamchatka, Russia, two groups of genetically indistinguishable microbes parted ways. They began evolving into different species - despite the fact that they still encountered one another in their acidic, boiling habitat and even exchanged some genes from time to time, researchers report. This is the first example of what the researchers call sympatric speciation in a microorganism.

  • Image of the interior of the cave and the massive trench with people standing at different levels and looking into the trench. The cave is dark and you can see the grid of guidelines used to plot the location of items found in the dig. There are bright worklights overhead.

    Cave excavation pushes back the clock on early human migration to Laos

    Fifteen years of archaeological work in the Tam Pa Ling cave in northeastern Laos has yielded a reliable chronology of early human occupation of the site, scientists report in the journal Nature Communications. The team’s excavations through the layers of sediments and bones that gradually washed into the cave and were left untouched for tens of thousands of years reveals that humans lived in the area for at least 70,000 years – and likely even longer.

  • Portrait of Jessica Brinkworth, standing facing the camera and smiling. She is outdoors on the U. of I. campus.

    Cell-autonomous immunity shaped human evolution

    Every human cell harbors its own defenses against microbial invaders, relying on strategies that date back to some of the earliest events in the history of life. Understanding this “cell-autonomous immunity” is essential to understanding human evolution and human medicine, researchers report.

  • Professor Ning Wang led a team that found that tumor-repopulating cancer cells can go dormant in stiffer tissues but wake up and multiply when placed in a softer environment.

    Cell mechanics may hold key to how cancer spreads and recurs

    CHAMPAIGN, Ill. - Cancer cells that break away from tumors to go looking for a new home may prefer to settle into a soft bed, according to new findings from researchers at the University of Illinois.

  • Cells direct membrane traffic by channel width, scientists say

    CHAMPAIGN, Ill. - For a glycerol molecule, a measly angstrom's difference in diameter is a road-closed sign: You can't squeeze through unless you are a sleek, water-molecule-sized sports car, say scientists at the University of Illinois at Urbana-Champaign.

  • Census of protein architectures offers new view of history of life

    CHAMPAIGN, Ill. - The present can tell you a lot about the past, but you need to know where to look. A new study appearing this month in Genome Research reveals that protein architectures - the three-dimensional structures of specific regions within proteins - provide an extraordinary window on the history of life.

  • The Center for One Health Illinois aims to integrate environmental, agricultural, and human and animal health studies and practice.

    Center integrates human, animal, environmental health

    CHAMPAIGN, lll. - The Center for One Health Illinois, established at the University of Illinois last year with a $250,000 grant from the U.S. Department of Agriculture, will receive another $500,000 in grants over several years from the USDA to pursue its mission of fostering collaborations and the free flow of information among those in the fields of medicine, public health, the environment and agriculture.

  • Susan Schantz (right), a professor of comparative biosciences at Illinois and an environmental toxicologist, will direct the new, NIH-funded Children's Environmental Health and Disease Prevention Research Center at Illinois. Comparative biosciences professor Jodi Flaws, a reproductive toxicologist, will act as associate director of the new center, which will investigate whether common plastics chemicals alter child development, cognition or behavior.

    Center to study effects of plastics chemicals on children's health

    CHAMPAIGN, lll. - A new research center based at the University of Illinois will investigate whether regular exposure to bisphenol A (BPA) and phthalates - chemicals widely used in plastics and other consumer products - can alter infant and adolescent development, cognition or behavior.

  • Chancellor, chemist elected to American Academy of Arts and Sciences

    CHAMPAIGN, Ill. - Richard Herman, the chancellor of the Urbana campus of the University of Illinois, and Jeffrey Moore, the Murchison-Mallory Professor of Chemistry at Illinois, have been elected to the American Academy of Arts and Sciences, the academy announced today.

  • Changes in brain, not age, determine one's ability to focus on task

    CHAMPAIGN, Ill. - When it comes to focusing on a task amid distractions, some folks more than 60 years old are as mentally sharp as 22-year-olds. Others struggle. Researchers at the Beckman Institute for Advanced Science and Technology at the University of Illinois at Urbana-Champaign have shed some light on why that is.

  • Chemical analysis of mushrooms shows their nutritional benefits

    CHAMPAIGN, Ill. - An analysis of previously uncharted chemical contents, mostly carbohydrates, in U.S.-consumed mushrooms shows that these fruity edible bodies of fungi could be tailored into dietary plans to help fill various nutritional needs.

  • Professor Kristopher Kilian led a research team that developed a chemical array to culture metastatic cancer cells so that different treatments can be tested on them.

    Chemical array draws out malignant cells to guide individualized cancer treatment

    Melanoma is a particularly difficult cancer to treat once it has metastasized, spreading throughout the body. University of Illinois researchers are using chemistry to find the deadly, elusive malignant cells within a melanoma tumor that hold the potential to spread.

  • Civil and environmental engineering professor Helen Nguyen has found that water-softening additives may increase the risk of pathogen release into drinking water by weakening the grip that bacteria have on pipe interiors.

    Chemicals that keep drinking water flowing may also cause fouling

    Many city drinking water systems add softening agents to keep plumbing free of pipe-clogging mineral buildup. According to new research, these additives may amplify the risk of pathogen release into drinking water by weakening the grip that bacteria – like those responsible for Legionnaires’ disease – have on pipe interiors.  

  • Chemist, entomologist among new fellows of arts and sciences academy

    CHAMPAIGN, Ill. - Chemist Peter Beak and entomologist Gene E. Robinson of the University of Illinois at Urbana-Champaign are among the 202 newly elected fellows and foreign honorary members of the American Academy of Arts and Sciences.

  • Chemist Kenneth L. Rinehart dies at 76

    CHAMPAIGN -Kenneth L. Rinehart, a chemistry professor at the University of Illinois at Urbana-Champaign who was internationally known for his research on organic compounds involved in biological activity, died Monday at his Urbana home after a long illness. He was 76.

  • Chickens may help aid in early detection of ovarian cancer

    Understanding and treatment of human ovarian cancer, known as the silent killer, may be a step closer thanks to some chickens at the UI. Ovarian cancer is the fourth leading cause of cancer deaths in women and unlike other cancers, its rate of mortality has not been reduced.

  • Chief of Illinois State Water Survey to discuss drought assessment

    CHAMPAIGN, Ill. -- Despite recent rains over parts of Illinois, drought conditions have worsened in central and southwestern regions of the state, say officials of the Illinois State Water Survey.

  • Yee Ming Khaw stands on the left, Makoto Inoue stands on the right.

    Childhood trauma could affect development, treatment of multiple sclerosis, mouse study finds

    Childhood trauma could affect the trajectory of multiple sclerosis development and response to treatment in adulthood, a new study in mice found.

    Mice that had experienced stress when young were more likely to develop the autoimmune disorder and less likely to respond to a common treatment, researchers at the University of Illinois Urbana-Champaign found. However, treatment that activated an immune-cell receptor mitigated the effects of childhood stress in the mice.

  • University of Illinois psychology professor and Beckman Institute director Art Kramer and his colleagues found differences in the brains of physically fit children and their less-fit peers.

    Children's brain development is linked to physical fitness

    CHAMPAIGN, lll. - Researchers have found an association between physical fitness and the brain in 9- and 10-year-old children: Those who are more fit tend to have a bigger hippocampus and perform better on a test of memory than their less-fit peers.

  • Children with ADHD benefit from time outdoors enjoying nature

    CHAMPAIGN, Ill. - Kids with attention deficit hyperactive disorder (ADHD) should spend some quality after-school hours and weekend time outdoors enjoying nature, say researchers at the University of Illinois at Urbana-Champaign.

  • Chill-tolerant hybrid sugarcane also grows at lower temperatures, team finds

    U.S. farmers have long hoped to extend sugarcane’s growing range northward from the Gulf coast, substantially increasing the land available for sugar and biofuels. Several hybrid canes developed in the 1980s have proved hardy in cooler climes, surviving overwinter as far north as Booneville, Arkansas. But until now, no one had tested whether these “miscanes,” as they are called, actually photosynthesize, and thus continue to grow, when the thermometer dips.

  • Chipmunks descended from ancestors that survived last ice age, scientists say

    CHAMPAIGN, Ill. - Well, nuts.

  • A cholesterol byproduct facilitates breast cancer’s spread by hijacking immune cells, a new University of Illinois study found. Pictured, from left: Postdoctoral researcher Amy Baek, professor Erik Nelson and breast cancer survivor Sarah Adams.

    Cholesterol byproduct hijacks immune cells, lets breast cancer spread

    A cholesterol byproduct facilitates breast cancer’s spread by hijacking immune cells, a new University of Illinois study found.

  • Professor Erik Nelson and graduate student Liqian Ma.

    Cholesterol metabolite causes immune system to attack T cells instead of breast cancer, study finds

    In breast cancer tumors, a molecule produced when the body breaks down cholesterol hijacks the myeloid immune cells that normally arm T cells to fight cancer, a new study in mice found. Instead, the hijacked myeloid cells disarm the T cells and even tell them to self-destruct.

  • Portrait of researcher.

    Cholesterol metabolite induces production of cancer-promoting vesicles

    Scientists report that a byproduct of cholesterol metabolism causes some cells to send out cancer-promoting signals to other cells. These signals are packaged in membrane-bound compartments called extracellular vesicles.

  • Christmas week snowstorm in Ohio river valley broke all records

    CHAMPAIGN, Ill. - Even though spring and warm-weather thoughts are here, a chilling, soon-to-be published report says that December's immense Midwest snowstorm was one to remember.

  • Institute for Genomic Biology director and animal sciences professor Harris Lewin and his colleagues found that different regions of chromosomes can have different evolutionary histories.

    Chromosome breakpoints contribute to genetic variation

    CHAMPAIGN, lll. - A new study reveals that - contrary to decades of evolutionary thought - chromosome regions that are prone to breakage when new species are formed are a rich source of genetic variation.

  • Chronic exposure to estradiol impairs some cognitive functions

    CHAMPAIGN, Ill. - University of Illinois researchers report this week that chronic exposure to estradiol, the main estrogen in the body, diminishes some cognitive functions. Rats exposed to a steady dose of estradiol were impaired on tasks involving working memory and response inhibition, the researchers found.

  • Researchers have demonstrated a new fabrication technique that allows them replicate the nanostructures found on cicada wings that make them water- and microbe-repellent.

    Cicada-inspired waterproof surfaces closer to reality, researchers report

    A multidisciplinary group that studies the physical and chemical properties of insect wings has demonstrated the ability to reproduce the nanostructures that help cicada wings repel water and prevent bacteria from establishing on the surface. The new technique – which uses commercial nail polish – is economical and straightforward, and the researchers said it will help fabricate future high-tech waterproof materials.

  • The wings of Megatibicen dorsatus, a prairie-dwelling cicada, are helping engineers design water-repellent surfaces.

    Cicada wings may inspire new surface technologies

    Researchers are looking to insects – specifically cicadas – for insight into the design of artificial surfaces with de-icing, self-cleaning and anti-fogging abilities. 

  • Cilia in the efferent ductules of the male reproductive tract don’t transport sperm, as was previously thought, but agitate the fluid to keep the sperm from aggregating, new research indicates. Rex Hess was a co-author on the study.

    Cilia beat to an unexpected rhythm in male reproductive tract, study in mice reveals

    Waves of undulating cilia drive several processes essential to life. They clear debris and mucus from the respiratory tract, move spinal fluid through the brain and transport embryos from the ovaries to the uterus for implantation. According to a new study in mice, however, cilia perform somewhat differently in the male reproductive tract.

  • A trail camera captured images of a fox in its den on the UW campus.

    'Citizen scientists' help track foxes, coyotes in urban areas

    As foxes and coyotes adapt to urban landscapes, the potential for encounters with humans necessarily goes up. A team of scientists is taking advantage of this fact to enlist the eyeballs and fingertips of humans – getting them to report online what they see in their own neighborhoods and parks.

  • Anthropologist Lisa J. Lucero found that illiterate Maya commoners found a way to record their own history - by burying it within their homes.

    Classic Maya history is embedded in commoners' homes

    CHAMPAIGN, lll. - They were illiterate farmers, builders and servants, but Maya commoners found a way to record their own history - by burying it within their homes. A new study of the objects embedded in the floors of homes occupied more than 1,000 years ago in central Belize begins to decode their story.

  • Click beetles can jump without the aid of their limbs when they are tipped onto their backsides. A team of University of Illinois researchers are examining this mechanism to engineer self-righting robots.

    Click beetles inspire design of self-righting robots

    Robots perform many tasks that humans can’t or don’t want to perform, getting around on intricately designed wheels and limbs. If they tip over, however, they are rendered almost useless. A team of University of Illinois mechanical engineers and entomologists are looking to click beetles, who can right themselves without the use of their legs, to solve this robotics challenge.

  • Don Wuebbles, the Harry E. Preble Professor of Atmospheric Sciences, was one of the contributors to the assessment of climate change in the U.S.

    Climate change already is having an impact in the Midwest and across the U.S.

    CHAMPAIGN, Ill. - Extreme weather, drought, heavy rainfall and increasing temperatures are a fact of life in many parts of the U.S. as a result of human-induced climate change, researchers report today in a new assessment. These and other changes will continue and likely increase in intensity into the future, the scientists found.

  • Climate change topic of annual Charles David Keeling lecture at U. of I.

    CHAMPAIGN,Ill. - Edward Maibach, a professor at George Mason University, will give a lecture in a series that honors Charles David Keeling, an analytical chemist at the University of Illinois and a member of the National Academy of Sciences.

  • Cloning techniques produce FDA-approved antibiotic

    CHAMPAIGN, Ill. - The successful synthesis of an antibiotic in a non-native host has provided a team of researchers at the University of Illinois at Urbana-Champaign with the potential for developing new treatments for bacterial infections.

  • Portrait of Gratton and Fabiani

    Cocoa flavanols boost brain oxygenation, cognition in healthy adults

    The brains of healthy adults recovered faster from a mild vascular challenge and performed better on complex tests if the participants consumed cocoa flavanols beforehand, researchers report.

  • Illinois professor Aron Barbey led a study that examined how cognitive cross-training affects skill learning.

    Cognitive cross-training enhances learning, study finds

    Just as athletes cross-train to improve physical skills, those wanting to enhance cognitive skills can benefit from multiple ways of exercising the brain, according to a comprehensive new study from University of Illinois researchers.

  • Jim Monti (right) a postdoctoral research associate in the lab of Illinois psychology professor Neal Cohen (left), developed a cognitive task that helps differentiate older adults with very early Alzheimer's disease from those experiencing normal aging.

    Cognitive test can differentiate between Alzheimer's and normal aging

    CHAMPAIGN, Ill. - Researchers have developed a new cognitive test that can better determine whether memory impairments are due to very mild Alzheimer's disease or the normal aging process.

  • Researchers developed a rapid sensing gel to measure a molecular marker of eye injury in a teardrop. From left: Carle opthamologist Dr. Laura Labriola, Illinois visiting scholar Ketan Dighe and professor Dipanjan Pan.

    Color-changing sensor detects signs of eye damage in tears

    A new point-of-care rapid-sensing device can detect a key marker of eye injury in minutes – a time frame crucial to treating eye trauma.  

    University of Illinois researchers developed a gel laden with gold nanoparticles that changes color when it reacts with a teardrop containing ascorbic acid, released from a wound to the eye. In a new study published in the journal Biosensors and Bioelectronics, the researchers used the sensor, called OjoGel, to measure ascorbic acid levels in artificial tears and in clinical samples of fluid from patients’ eyes.