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Veterinary medicine A new study of mice by scientists at the University of Illinois raises concerns about the potential impact that long-term exposure to genistein prior to conception may have on fertility and pregnancy. The study was conducted by, from left, food science and human nutrition professor William G. Helferich, comparative biosciences professor Jodi A. Flaws and animal sciences research specialist James A. Hartman.

Study in mice finds dietary levels of genistein may adversely affect female fertility

CHAMPAIGN, Ill. — Exposure to the phytoestrogen genistein prior to conception may adversely affect female fertility and pregnancy outcomes, depending on the dosage and duration of exposure, a new study in mice suggests. Chronic preconception exposure to genistein affected pregnancy rates in mice and was associated with prolonged labor, smaller litters and pups, and higher […]

Expert viewpoints Professor Jason Pieper

Antibiotic-resistant infections in pets: What now?

Nearly every day on the job, veterinary clinical medicine professor Dr. Jason Pieper, a veterinary dermatologist, sees antibiotic-resistant bacterial infections in cats, dogs and other pets. This is not just a local phenomenon; nationally, rates of antibiotic-resistant infections in companion animals are rising at an alarming rate. Pieper spoke to News Bureau life sciences editor […]

Veterinary medicine In a new study of more than 1,400 critically ill calves with diarrhea, Peter D. Constable and his colleagues found that clinical signs of disease were better predictors of mortality than the laboratory data that clinicians have relied upon historically. Constable is the dean of the College of Veterinary Medicine at the University of Illinois.

Paper: Clinical signs best predictors of mortality in critically ill calves

CHAMPAIGN, Ill. — Clinical signs such as gastrointestinal problems or septic arthritis may be better predictors of mortality in neonatal calves with diarrhea than blood pH levels and other laboratory findings, a new study suggests. The research also may finally resolve a century-old debate among scientists about the blood pH levels needed to sustain life […]

Life Sciences Veterinary Medicine Graduate student Josephine Watson, professor Aditi Das, graduate student Megan Corbett, professor Kristopher Kilian and their colleagues discovered an enzymatic pathway that converts omega-3-derived endocannabinoids into more potent anti-inflammatory molecules.

Study: Omega-3 fatty acids fight inflammation via cannabinoids

CHAMPAIGN, Ill. — Chemical compounds called cannabinoids are found in marijuana and also are produced naturally in the body from omega-3 fatty acids. A well-known cannabinoid in marijuana, tetrahydrocannabinol, is responsible for some of its euphoric effects, but it also has anti-inflammatory benefits. A new study in animal tissue reveals the cascade of chemical reactions […]

Life Sciences Veterinary Medicine Fred Kummerow, a professor of comparative biosciences at the University of Illinois, continued his research for more than seven decades. Kummerow died May 31 at his home in Urbana.

Fred A. Kummerow, successful crusader against trans fats, dies at 102

CHAMPAIGN, Ill. — Fred A. Kummerow, a pioneer in the study of dietary contributors to heart disease who led a decades-long crusade to remove trans fats from the food supply, died Wednesday, May 31, at his home in Urbana, Illinois. He was 102. Kummerow was a professor of comparative biosciences who maintained a laboratory at […]

Veterinary medicine

New MRI opens door to innovative veterinary research and care

CHAMPAIGN, Ill. — Advances in magnetic resonance imaging have transformed medicine over the last several decades. Unfortunately, this technology is rarely available to veterinarians. The University of Illinois College of Veterinary Medicine is now one of a few veterinary research and clinical care schools in the U.S. with a state-of-the-art 3-Tesla MRI facility. The recently […]

Life Sciences Veterinary Medicine

Scientists test nanoparticle drug delivery in dogs with osteosarcoma

CHAMPAIGN, Ill. — At the University of Illinois, an engineer teamed up with a veterinarian to test a bone cancer drug delivery system in animals bigger than the standard animal model, the mouse. They chose dogs – mammals closer in size and biology to humans – with naturally occurring bone cancers, which also are a […]

Life Sciences Veterinary Medicine

Report: A host of common chemicals endanger child brain development

CHAMPAIGN, Ill. — In a new report, dozens of scientists, health practitioners and children’s health advocates are calling for renewed attention to the growing evidence that many common and widely available chemicals endanger neurodevelopment in fetuses and children of all ages. The chemicals that are of most concern include lead and mercury; organophosphate pesticides used […]

Education

With online games, high school students learn how to rein in disease outbreaks

CHAMPAIGN, Ill. — High school students investigate Ebola-like outbreaks and administer vaccines through Outbreak!, a new summer course at Illinois that uses online games to encourage critical thinking about fighting infectious diseases.  Dr. Yvette Johnson-Walker, an epidemiologist and a clinical instructor in the department of veterinary clinical medicine at the U. of I., leads the […]

Expert viewpoints Dr. Adam Stern

When veterinarians become crime scene investigators

Just as police and forensic pathologists investigate crimes involving human perpetrators and victims, veterinary pathologists are sometimes called upon to determine whether – and how, and by whom – animals were abused or killed by humans. They also investigate injuries or deaths caused by animals. U. of I. veterinary diagnostic laboratory professor Dr. Adam Stern, […]

Business Life Sciences Veterinary Medicine

Human trials of cancer drug PAC-1 continue with new investment

CHAMPAIGN, Ill. — Clinical trials of the anti-cancer agent PAC-1 are continuing to expand, thanks to a $7 million angel investment from an anonymous contributor who originally invested $4 million to help get the compound this far in the drug-approval pipeline. The U.S. Food and Drug Administration also granted PAC-1 orphan drug status for the […]

Engineering Life Sciences Physical Sciences Veterinary Medicine Illinois researchers found that the shape of a tumor may play a role in how cancer cells become primed to spread. From left: materials science and engineering professor Kristopher Kilian, graduate student Junmin Lee and veterinary medicine professor Timothy Fan.

Shape of tumor may affect whether cells can metastasize

CHAMPAIGN, Ill. — Only a few cells in a cancerous tumor are able to break away and spread to other parts of the body, but the curve along the edge of the tumor may play a large role in activating these tumor-seeding cells, according to a new University of Illinois study. Using engineered tissue environments […]

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