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Veterinary medicine Bottlenose dolphins found on Gulf of Mexico beaches after the 2010 Deepwater Horizon oil spill had severe lung and adrenal gland abnormalities consistent with petroleum product exposure, researchers report.

Researchers link dolphin deaths to Deepwater Horizon oil spill

CHAMPAIGN, Ill. — Dolphins found stranded on Gulf of Mexico beaches following the 2010 Deepwater Horizon oil spill were much more likely to have severe lung and adrenal gland damage “consistent with petroleum product exposure” than dolphins stranded elsewhere and prior to the spill, researchers report. One in five dolphins from the spill zone also […]

Life sciences In a study of mice, comparative biosciences professor Jodi Flaws and her colleagues linked BPA exposure during pregnancy to reproductive problems in the next three generations.

BPA exposure in pregnant mice affects fertility in three generations

CHAMPAIGN, Ill. – When scientists exposed pregnant mice to levels of bisphenol A equivalent to those considered safe in humans, three generations of female mouse offspring experienced significant reproductive problems, including declines in fertility, sexual maturity and pregnancy success, the scientists report in the journal Toxicology and Applied Pharmacology. Bisphenol A, an industria l chemical, […]

Life sciences University of Illinois chemistry professor Paul Hergenrother, left, and veterinary clinical medicine professor Timothy Fan tested an anti-cancer compound in pet dogs that will be used in human clinical trials.

Cancer drug first tested in pet dogs begins human trials

CHAMPAIGN, Ill. – A new drug that prompts cancer cells to self-destruct while sparing healthy cells is now entering phase I clinical trials in humans. The drug, called PAC-1, first showed promise in the treatment of pet dogs with spontaneously occurring cancers, and is still in clinical trials in dogs with osteosarcoma. “The compound was […]

Life sciences Muskrats in central Illinois are being exposed to toxoplasmosis, a disease spread by cats.

In Illinois, muskrats and minks harbor toxoplasmosis, a cat disease

CHAMPAIGN, Ill. – A new study of muskrats and minks in central Illinois indicates that toxoplasmosis, a disease spread by cats, is moving rapidly through the landscape and contaminating local waterways. Researchers found antibodies for Toxoplasma gondii, the parasite that causes toxoplasmosis, in 18 of 30 muskrats and 20 of 26 minks tested for the […]

Life sciences An interdisciplinary research team developed a new approach to treating endometriosis. The team includes, clockwise, from back left: molecular and integrative physiology professor Milan Bagchi, chemistry professor John Katzenellenbogen, visiting research scientist Ping Gong, molecular and integrative physiology professor Benita Katzenellenbogen, postdoctoral fellow Yiru Chen, research scientist Yuechao Zhao, and comparative biosciences professor CheMyong Ko.

New drug compounds show promise against endometriosis

CHAMPAIGN, Ill. – Two new drug compounds – one of which has already proven useful in a mouse model of multiple sclerosis – appear to be effective in treating endometriosis, a disorder that, like MS, is driven by estrogen and inflammation, scientists report in Science Translational Medicine. The researchers hope to eventually use the new […]

Life sciences After experiencing power outages during a 2007 ice storm in Springfield, Missouri, Dickerson Park Zoo officials improved their backup power and heating systems to keep animals - like Henry, pictured here -- safe and warm.

Flu at the zoo and other disasters: Experts help animal exhibitors prepare for the worst

CHAMPAIGN, Ill. – Here are three disaster scenarios for zoo or aquarium managers: One, a wildfire lunges towards your facility, threatening your staff and hundreds of zoo animals. Two, hurricane floodwaters pour into your basement, where more than 10,000 exotic fish and marine mammals live in giant tanks. Three, local poultry farmers report avian influenza […]

Life sciences An emerging fungal disease threatens the last eastern massasauga rattlesnake population in Illinois.

Scientists gear up to fight deadly snake fungal disease

CHAMPAIGN, Ill. – Researchers have developed a faster and more accurate way to test for infection with Ophidiomyces ophiodiicola, a fungus that is killing snakes in the Midwest and eastern United States. The test also allows scientists to monitor the progression of the infection in living snakes. The researchers reported on the test at the […]

Life sciences Regular exposure to artificial ultraviolet B light for two weeks doubled rabbits' serum vitamin D levels, the researchers found.

Rabbits kept indoors could be vitamin D deficient

CHAMPAIGN, Ill. – Rabbits that remain indoors may suffer from a lack of vitamin D, researchers report in a new study. In rabbits kept as pets or used in laboratory studies, the deficiency could lead to dental problems, undermine their cardiovascular health, weaken their immune systems and skew scientific findings. The study found that regular […]

Life sciences Fred Kummerow, a professor of comparative biosciences at the University of Illinois, reports that LDL cholesterol results from a simple dietary deficiency.

‘Bad cholesterol’ indicates an amino acid deficiency, researcher says

CHAMPAIGN, Ill. – Low-density lipoprotein (LDL), the “bad cholesterol” that doctors consider a sign of potential heart disease, is merely a marker of a diet lacking all of the essential amino acids, says University of Illinois comparative biosciences professor Fred Kummerow, 99, a longtime opponent of the medical establishment’s war on cholesterol. While writing about […]

Veterinary medicine Stuart C. Clark-Price, a specialist in anesthesiology and pain management in the U. of I. Veterinary Teaching Hospital, is leading a multiuniversity research project aimed at developing treatment protocols that help horses get back on their hooves quickly and safely after surgery.

Cellphone technology helps horses recover from surgery

CHAMPAIGN, Ill. – Technology that’s used in smartphones and other electronic devices also is being used by veterinarians at the University of Illinois to help horses recover safely from anesthesia. Accelerometers – portable data recorders that capture information on motion, vibration and impact – are frequently affixed to shipping containers when transporting delicate scientific instruments […]

Campus life

U. of I. designated one of first Veterinary Trauma Centers

The small animal emergency service at the U. of I. Veterinary Teaching Hospital is one of nine U.S. veterinary hospitals and clinics to be provisionally designated as a Veterinary Trauma Center by the American College of Veterinary Emergency and Critical Care. The new designation is part of an initiative to improve treatment outcomes of animal […]

Veterinary medicine A better mousetrap The VetMouseTrap, a restraint device developed by veterinary radiologist Robert T. O'Brien, is enabling clinicians to conduct CT scans on patients that couldn't be scanned previously, leading to faster diagnosis and treatment of life-threatening conditions.

‘Mouse trap’ allows vets to make faster diagnoses, without anesthesia

CHAMPAIGN, Ill. – Advancements in the use of computed tomography (also known as CT) imaging by researchers at the University of Illinois Veterinary Teaching Hospital are enabling them to diagnose life-threatening conditions in dogs and cats faster, dramatically affecting the course, outcomes and costs of treatment. With faster diagnoses, aggressive, appropriate treatment can begin within […]

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