Veterinary Medicine
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New antifungal molecule kills fungi without toxicity in human cells, mice
CHAMPAIGN, Ill. — A new antifungal molecule, devised by tweaking the structure of prominent antifungal drug Amphotericin B, has the potential to harness the drug’s power against fungal infections while doing away with its toxicity, researchers at the University of Illinois Urbana-Champaign and collaborators at the University of Wisconsin-Madison report in the journal Nature. Amphotericin B, […]
IKIDS child health research gets another boost in funding
CHAMPAIGN, Ill. — Seven years after an initial $17.9 million award from the National Institutes of Health, the Illinois Kids Development Study at the University of Illinois Urbana-Champaign will receive approximately $13.7 million – awarded in two phases – to continue its work for another seven years. The money coming to Illinois is part of […]
T-cells infiltrate brain, cause respiratory distress in condition affecting the immunocompromised
CHAMPAIGN, Ill. — When an immunocompromised person’s system begins to recover and produce more white blood cells, it’s usually a good thing – unless they develop a potentially deadly inflammatory condition. New research from the University of Illinois Urbana-Champaign has found that the pulmonary distress often associated with the condition is caused not by damage […]
GABA receptors in brain could be targets to treat depression and its cognitive symptoms
CHAMPAIGN, Ill. — Depression is a complex condition correlated with multiple differences in brain function and mechanisms. A new paper spanning known data about the neurotransmitter GABA and its principal receptors showcases evidence of the receptors’ importance in depression and potential as therapeutic targets. Based on evidence from research on the receptors’ function in the […]
Team develops all-species coronavirus test
CHAMPAIGN, Ill. — In an advance that will help scientists track coronavirus variants in wild and domesticated animals, researchers report they can now detect exposure to the SARS-CoV-2 virus in any animal species. Most coronavirus antibody tests require specialized chemical reagents to detect host antibody responses against the virus in each species tested, impeding research […]
Smart surgical implant coatings provide early failure warning while preventing infection
CHAMPAIGN, Ill. — Newly developed “smart” coatings for surgical orthopedic implants can monitor strain on the devices to provide early warning of implant failures while killing infection-causing bacteria, University of Illinois Urbana-Champaign researchers report. The coatings integrate flexible sensors with a nanostructured antibacterial surface inspired by the wings of dragonflies and cicadas. In a new […]
First test of anti-cancer agent PAC-1 in human clinical trials shows promise
CHAMPAIGN, Ill. — A phase I clinical trial of PAC-1, a drug that spurs programmed cell death in cancer cells, found only minor side effects in patients with end-stage cancers. The drug stalled the growth of tumors in the five people in the trial with neuroendocrine cancers and reduced tumor size in two of those […]
Study explores unusual interaction between viruses, live vaccines
CHAMPAIGN, Ill. — A study of a herpes virus that infects chickens offers new insights into potentially problematic interactions between vaccines made from live viruses and the viruses they are meant to thwart. Reported in the journal Virulence, the study offers direct evidence that a vaccine and virus can infect the same cells in living […]
SHIELD program a model for effective pandemic management, data show
CHAMPAIGN, Ill. — In the fall of 2020, the University of Illinois Urbana-Champaign welcomed students back for in-person instruction amid the powerful first wave of the COVID-19 pandemic. The university successfully maintained operations throughout the semester – with zero COVID-19-related deaths or hospitalizations in the campus community – thanks to its “SHIELD: Target, Test, Tell” […]
Can pet dogs be infected with coronavirus?
On Feb. 6, a team led by pathobiology professor Ying Fang, a virologist at the University of Illinois Urbana-Champaign, diagnosed a pet dog in Chicago with infection with SARS-CoV-2, the virus that causes COVID-19 in humans. This is the first dog in Illinois to test positive for the coronavirus. Fang spoke with News Bureau life […]
Do kids need a COVID-19 vaccine?
Children ages 5 to 11 now can receive a COVID-19 vaccine from Pfizer-BioNTech under emergency use authorization from the Food and Drug Administration and recommendation from the Centers for Disease Control and Prevention. Rebecca Lee Smith, an epidemiologist and professor in the Carle Illinois College of Medicine and the College of Veterinary Medicine at the […]
Which animals can catch the coronavirus?
On Oct. 6, the U.S. Department of Agriculture’s National Veterinary Services Laboratories announced confirmation of SARS-CoV-2 – the virus that causes COVID-19 – in two previously uninfected animal species at a zoo in Illinois. Dr. Leyi Wang, a virologist and professor of veterinary medicine at the University of Illinois Urbana-Champaign, first tested the samples in the university’s […]