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Long-term alcohol use suspends liver cells in limbo, preventing regeneration
Excessive alcohol consumption can disrupt the liver’s unique regenerative abilities by trapping cells in limbo between their functional and regenerative states, even after a patient stops drinking, researchers at University of Illinois Urbana-Champaign and collaborators found in a new study. This in-between state is a result of inflammation disrupting how RNA is spliced during the protein-making process, the researchers found, providing scientists with new treatment pathways to explore for the deadly disease.
High-volume antibody testing platform could accelerate disease research and treatment development
CHAMPAIGN, Ill. — Antibodies are the critical targeting agents of the immune system and the crux of immune therapy and vaccine development, but studying them is slow, expensive and labor-intensive. Now, researchers at the University of Illinois Urbana-Champaign have developed a new high-volume method that can rapidly build and test large numbers of antibodies at […]
Kidney fibrosis linked to molecule made by gut bacteria
A molecule made by bacteria in the gut can hitch a ride to the kidneys, where it sets off a chain reaction of inflammation, scarring and fibrosis — a serious complication of diabetes and a leading cause of kidney failure — according to a new study from researchers at the University of Illinois Urbana-Champaign and Mie University in Japan. The group also developed a new antibody that could counter it.
Paper: Decarbonize agriculture by expanding policies aimed at low-carbon biofuels
CHAMPAIGN, Ill. — A team of agricultural economists, environmental scientists and policy experts envisions a path toward a carbon-neutral agricultural future by expanding the reach of policies designed to promote low-carbon biofuels for transportation and aviation. In a new paper in the journal Science, the researchers propose policies that would reward farmers for adopting “climate-smart” […]
Illinois team updates state threatened, endangered plant species rankings
CHAMPAIGN, Ill. — Scientists from the Illinois Natural History Survey and the Illinois Department of Natural Resources have updated the state conservation status ranks, or S-ranks, of threatened and endangered plants in Illinois. The update includes some plants not recorded in the state for decades and finds many that, while still threatened, are doing better […]
Illinois information sciences researchers develop AI safety testing methods
CHAMPAIGN, Ill. — Large language models are built with safety protocols designed to prevent them from answering malicious queries and providing dangerous information. But users can employ techniques known as “jailbreaks” to bypass the safety guardrails and get LLMs to answer a harmful query. Researchers at the University of Illinois Urbana-Champaign are examining such vulnerabilities […]
Can nuclear energy be produced on the moon?
CHAMPAIGN, Ill. — NASA’s announcement that it will accelerate the Fission Surface Power program, targeting deployment of a 100-kilowatt nuclear reactor on the moon by 2030, represents an ambitious acceleration of extraterrestrial energy strategy. From 2021-24, Katy Huff, a professor of nuclear, plasma and radiological engineering at the University of Illinois Urbana-Champaign, held multiple positions […]
What happens if the landmark rule on emissions is repealed?
Repealing the “endangerment finding” would nullify the EPA’s ability to regulate greenhouse gas emissions under the Clean Air Act and incur high long-term costs to health and property, says climate expert Donald Wuebbles, professor emeritus at the University of Illinois Urbana-Champaign.
Brewed chicken protein made by precision fermentation tested in pet food
CHAMPAIGN, Ill. — In a groundbreaking new project, scientists used precision fermentation to produce brewed chicken protein and evaluated it for use in pet food. Dogs that consumed the protein in their kibble during a six-month study had beneficial digestive effects, the researchers found. Scientists at the University of Illinois Urbana-Champaign and Bond Pet Foods, […]
NSF reinvests in Molecule Maker Lab Institute, AI tools to solve chemistry’s challenges
With a new five-year, $15 million award, the U.S. National Science Foundation has renewed its support of the Molecule Maker Lab Institute.
Study identifies gene clusters in rhizobia linked to robust legume growth
CHAMPAIGN, Ill. — In a new study, scientists used nearly every tool in their toolkit — genomics, transcriptomics, greenhouse experiments and advanced statistical methods — to gain new insight into the complex chemical interactions that take place in underground root nodules, where legumes like soybeans exchange vital nutrients with soil microbes called rhizobia. Reported in […]
Map-making neurons change even in familiar settings, study finds
CHAMPAIGN, Ill. — Neurobiologists at Northwestern University and the University of Illinois Urbana-Champaign found the brain’s internal GPS changes each time mice navigate a familiar, static environment. Even when a mouse walks the same path every day — and the path and surrounding conditions remain identical — each journey activates different “map-making” neurons in the […]